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膀胱乳头状瘤中乳头瘤病毒结构抗原的免疫组织化学显示

Immunohistochemical demonstration of papillomavirus structural antigen in urinary bladder papillary tumors.

作者信息

Serio G, Pioselli F, Galli L

机构信息

Servizi di anatomia patologica, Ospedali di Saronno (Varese), Magenta, Milano.

出版信息

Pathologica. 1990 Sep-Oct;82(1081):499-505.

PMID:1964207
Abstract

Clear cells with characteristic features of koilocytotic atypia (perinuclear clear zone, peripheral cytoplasmic condensation and hyperchromatic nuclei), were found in 35 out of 744 urothelial papillary tumors (UPT) of the human bladder. Using a peroxidase-antiperoxidase staining technique, papillomavirus common structural antigen was detected in six of the samples studied. The results suggests that urinary bladder tumors like some other genital cancer, may be linked to papillomavirus infection.

摘要

在744例人膀胱尿路上皮乳头状瘤(UPT)中,有35例发现了具有凹空细胞非典型特征(核周透明区、外周胞质浓缩和核深染)的透明细胞。采用过氧化物酶 - 抗过氧化物酶染色技术,在所研究的6个样本中检测到乳头瘤病毒共同结构抗原。结果表明,膀胱肿瘤与其他一些生殖器癌症一样,可能与乳头瘤病毒感染有关。

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Immunohistochemical demonstration of papillomavirus structural antigen in urinary bladder papillary tumors.膀胱乳头状瘤中乳头瘤病毒结构抗原的免疫组织化学显示
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引用本文的文献

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Detection of human papillomavirus DNA sequences in cancer of the urinary bladder by in situ hybridisation and polymerase chain reaction.通过原位杂交和聚合酶链反应检测膀胱癌中的人乳头瘤病毒DNA序列。
Genitourin Med. 1995 Aug;71(4):231-3. doi: 10.1136/sti.71.4.231.