Schmidt A, Roth N, Herr M
Institute of Neurobiology and Brain Research, GDR Academy of Sciences, Magdeburg.
Zh Vyssh Nerv Deiat Im I P Pavlova. 1990 Sep-Oct;40(5):850-5.
On the basis of contemporary knowledge on close functional connections between respiratory and cardiovascular afferents a computerized experimental device was developed by means of which central information processing can be studied in dependence on respiration phase and the level of baroreceptor activity. In all the examined parameters (time of motor reaction of two hands, latency of eye-lid reflex) the greatest changes were observed at maximum baroreceptor activity. These changes were clearly distinguished by direction during the phases of inhalation and exhalation. Such effect is probably based on the fact that the influence of cardiovascular afferents on the level of central activity is modulated in respiration rhythm through the mechanism of breath "gating" of postsynaptic STN structures.
基于当前关于呼吸和心血管传入神经之间紧密功能联系的知识,开发了一种计算机化实验装置,借助该装置可以根据呼吸阶段和压力感受器活动水平来研究中枢信息处理过程。在所有检测参数(双手的运动反应时间、眼睑反射潜伏期)中,最大的变化出现在压力感受器活动最强时。在吸气和呼气阶段,这些变化在方向上有明显区别。这种效应可能基于这样一个事实,即心血管传入神经对中枢活动水平的影响通过突触后丘脑底核结构的呼吸“门控”机制在呼吸节律中得到调节。