胎膜早破：晚期早产儿的临床结局

Preterm premature rupture of membranes: clinical outcomes of late-preterm infants.

作者信息

Mateus Julio, Fox Karin, Jain Sangeeta, Jain Sunil, Latta Richard, Cohen Jerry

机构信息

Department of Obstetrics and Gynecology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-0587, USA.

出版信息

Clin Pediatr (Phila). 2010 Jan;49(1):60-5. doi: 10.1177/0009922809342460. Epub 2009 Jul 30.

DOI:10.1177/0009922809342460

PMID:19643979

Abstract

OBJECTIVE

To determine gestational age-specific neonatal outcomes of late preterm infants delivered as a consequence of premature rupture of membranes (PROM).

METHODS

Retrospective cohort study of infants born to women delivered electively due to preterm PROM between 34(0/7) and 36(6/7) weeks of gestation. Neonatal outcomes were compared between those delivered at 34(0/7) to 34( 6/7) weeks, at 35(0/7) to 35(6/7) weeks, and at 36( 0/7) to 36(6/7) weeks.

RESULTS

192 infants were identified. The 34(0/7) to 34(6/7) week infants had significantly higher neonatal intensive care admission rate (72.5%) compared to those at 35( 0/7) to 35(6/7) weeks (22.8%) and at 36 to 36(6/7) weeks (17.8%) (P < .05). Neonatal respiratory distress syndrome was significantly higher at 34(0/7) to 34(6/7) weeks (35.4%) compared with 35(0/7) to 35(6/7) week and 36(0/7) to 36( 6/7) week infants (10.5% and 4.1%; P < .05). The longest hospitalization occurred in the 34(0/7) to 34(6/7) week infants (248.5 +/- 20.0 hours).

CONCLUSION

Substantial short-term morbidity occurred in late preterm infants. The greatest number of complications affected infants born at 34(0/7) to 34(6/7) weeks.

摘要

目的

确定因胎膜早破（PROM）而分娩的晚期早产儿的孕周特异性新生儿结局。

方法

对因早产PROM在妊娠34(0/7)至36(6/7)周期间择期分娩的妇女所生婴儿进行回顾性队列研究。比较在34(0/7)至34(6/7)周、35(0/7)至35(6/7)周以及36(0/7)至36(6/7)周分娩的婴儿的新生儿结局。

结果

共识别出192例婴儿。与35(0/7)至35(6/7)周（22.8%）和36至36(6/7)周（17.8%）分娩的婴儿相比，34(0/7)至34(6/7)周分娩的婴儿新生儿重症监护病房入院率显著更高（72.5%）（P <.05）。34(0/7)至34(6/7)周分娩的婴儿新生儿呼吸窘迫综合征发生率显著高于35(0/7)至35(6/7)周以及36(0/7)至36(6/7)周分娩的婴儿（分别为35.4%、10.5%和4.1%；P <.05）。住院时间最长的是34(0/7)至34(6/7)周分娩的婴儿（248.5 +/- 20.0小时）。