托伐普坦
Tolvaptan.
作者信息
Ghali Jalal K, Hamad Bashar, Yasothan Uma, Kirkpatrick Peter
机构信息
Harper University Hospital, 3990 John R Street, 9 Webber Core, Detroit, MI 48201, USA.
出版信息
Nat Rev Drug Discov. 2009 Aug;8(8):611-2. doi: 10.1038/nrd2946.
DOI:10.1038/nrd2946
PMID:19644472
Abstract
In May 2009, tolvaptan (Samsca; Otsuka), a selective vasopressin V(2) receptor antagonist, was approved by the US FDA for the treatment of clinically significant hypervolaemic and euvolaemic hyponatraemia.
摘要
2009年5月，选择性血管加压素V(2)受体拮抗剂托伐普坦（Samsca；大冢制药）获美国食品药品监督管理局批准，用于治疗具有临床意义的高容量性和等容量性低钠血症。
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