Genetic correction of hematopoiesis in Fanconi anemia: the case for a non-HSC-autonomous defect.
作者信息
Skinner Amy M, Kurre Peter
机构信息
Department of Pediatrics, Papé Family Pediatric Research Institute, Oregon Health and Science University, Portland, Oregon 97239, USA.
出版信息
Mol Ther. 2009 Aug;17(8):1313-5. doi: 10.1038/mt.2009.138.
Abstract
摘要
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本文引用的文献
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Mol Ther. 2009 Jun;17(6):1083-92. doi: 10.1038/mt.2009.26. Epub 2009 Mar 10.
2
Ectopic HOXB4 overcomes the inhibitory effect of tumor necrosis factor-{alpha} on Fanconi anemia hematopoietic stem and progenitor cells.异位HOXB4克服肿瘤坏死因子-α对范可尼贫血造血干细胞和祖细胞的抑制作用。
Blood. 2009 May 21;113(21):5111-20. doi: 10.1182/blood-2008-09-180224. Epub 2009 Mar 6.
3
Mesenchymal stem/progenitor cells promote the reconstitution of exogenous hematopoietic stem cells in Fancg-/- mice in vivo.间充质干/祖细胞促进Fancg基因敲除小鼠体内外源性造血干细胞的重建。
Blood. 2009 Mar 5;113(10):2342-51. doi: 10.1182/blood-2008-07-168138. Epub 2009 Jan 7.
4
Defective homing is associated with altered Cdc42 activity in cells from patients with Fanconi anemia group A.在A型范可尼贫血患者的细胞中，归巢缺陷与Cdc42活性改变有关。
Blood. 2008 Sep 1;112(5):1683-6. doi: 10.1182/blood-2008-03-147090. Epub 2008 Jun 18.
5
Uncertainty in the niches that maintain haematopoietic stem cells.维持造血干细胞的生态位中的不确定性。
Nat Rev Immunol. 2008 Apr;8(4):290-301. doi: 10.1038/nri2279. Epub 2008 Mar 7.
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Cell polarity and asymmetric cell division within human hematopoietic stem and progenitor cells.人类造血干细胞和祖细胞中的细胞极性与不对称细胞分裂。
Cells Tissues Organs. 2008;188(1-2):116-26. doi: 10.1159/000112842. Epub 2007 Dec 21.
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No place like home: anatomy and function of the stem cell niche.没有比家更好的地方：干细胞微环境的解剖结构与功能
Nat Rev Mol Cell Biol. 2008 Jan;9(1):11-21. doi: 10.1038/nrm2319.
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Engineering targeted viral vectors for gene therapy.工程化用于基因治疗的靶向病毒载体。
Nat Rev Genet. 2007 Aug;8(8):573-87. doi: 10.1038/nrg2141. Epub 2007 Jul 3.
9
Inflammatory ROS promote and cooperate with the Fanconi anemia mutation for hematopoietic senescence.炎症性活性氧促进范可尼贫血突变并与之协同作用导致造血衰老。
J Cell Sci. 2007 May 1;120(Pt 9):1572-83. doi: 10.1242/jcs.003152. Epub 2007 Apr 3.
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Therapeutic targeting of a stem cell niche.干细胞微环境的治疗靶向
Nat Biotechnol. 2007 Feb;25(2):238-43. doi: 10.1038/nbt1281. Epub 2007 Jan 21.
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