Department of Traumatology, TU Munich, Klinikum rechts der Isar, Munich, Germany.
Langenbecks Arch Surg. 2009 Nov;394(6):985-97. doi: 10.1007/s00423-009-0546-0. Epub 2009 Jul 31.
Stem cells are one of the most fascinating areas in regenerative medicine today. They play a crucial role in the development and regeneration of human life and are defined as cells that continuously reproduce themselves while maintaining the ability to differentiate into various cell types. Stem cells are found at all developmental stages, from embryonic stem cells that differentiate into all cell types found in the human body to adult stem cells that are responsible for tissue regeneration. The general opinion postulates that clinical therapies based on the properties of stem cells may have the potential to change the treatment of degenerative diseases or important traumatic injuries in the "near" future. We here briefly review the literature in particularly for the liver, heart, kidney, cartilage, and bone regeneration.
干细胞是当今再生医学中最引人关注的领域之一。它们在人类生命的发育和再生中起着至关重要的作用,被定义为能够持续自我复制并具有分化为多种细胞类型能力的细胞。干细胞存在于所有发育阶段,从能够分化为人体所有细胞类型的胚胎干细胞,到负责组织再生的成体干细胞。一般观点假设,基于干细胞特性的临床疗法可能有潜力在“不久的将来”改变退行性疾病或重要创伤性损伤的治疗方法。在这里,我们简要地综述了特别是在肝脏、心脏、肾脏、软骨和骨骼再生方面的文献。