McMillan Hugh J, Darras Basil T, Kang Peter B, Saleh Firas, Jones H Royden
Department of Neurology, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA.
Muscle Nerve. 2009 Nov;40(5):860-3. doi: 10.1002/mus.21401.
Pediatric monomelic amyotrophy may present a diagnostic challenge. This is particularly true for immigrant or adopted children who have little or no available medical history. We present clinical and electrophysiological data from 11 children with monomelic amyotrophy who had electrophysiological evidence of a unilateral or profoundly asymmetric motor neuronopathy. The cause of amyotrophy in each case is most consistent with prior: (1) wildtype poliovirus myelitis; (2) "polio-like" virus myelitis, or (3) vaccine associated paralytic poliomyelitis.
小儿单肢肌萎缩可能带来诊断挑战。对于几乎没有或完全没有可用病史的移民儿童或领养儿童而言尤其如此。我们展示了11名单肢肌萎缩患儿的临床和电生理数据，这些患儿具有单侧或极度不对称运动神经元病的电生理证据。每例肌萎缩的病因最符合既往的：(1)野生型脊髓灰质炎病毒脊髓炎；(2)“类脊髓灰质炎”病毒脊髓炎，或(3)疫苗相关麻痹性脊髓灰质炎。
