Zhou Tian-Nong, Tang Li-Hai, Huang Shi-Chong, Lu Dan-Dan, Wang Yan, Liu Liang-Feng, Lai Ping, Ye Mu-Rong
College of Chinese Traditional Medicine, Guangzhou University of TCM, Guangzhou 510405, China.
Zhong Yao Cai. 2009 Apr;32(4):571-4.
To observe the antitussive and antiasthmatic effects of Radix Fici Hirtae (RFH).
Antitussive effects were observed by ammonia water steaming test in mice and by citric acid test in guinea pigs. Antiasthmatic actions in guinea pigs were observed by histamine and acetylcholine ultrasonic atomization test, involved isolated guinea pig tracheal smoth muscle experiment and anaphylactic shock of guinea pigs.
RFH decreased the frequency of cough induced by ammonia in mice and by citric acid in guinea pig, prolonged the latent period of cough and inhibited the experimental asthma by histamine and acetylcholine solution in conscious guinea pigs, antagonisted the contraction of tracheal smooth muscle by histamine phosphate in guinea pigs and could compete anaphylactic shock in guinea pigs.
RFH has obvious antitussive and antiasthmatic effects.
观察五指毛桃的镇咳、平喘作用。
采用氨水引咳法观察其对小鼠的镇咳作用，采用枸橼酸引咳法观察其对豚鼠的镇咳作用；采用组胺和乙酰胆碱超声雾化引喘法、豚鼠离体气管平滑肌实验、豚鼠过敏性休克实验观察其对豚鼠的平喘作用。
五指毛桃能减少氨水所致小鼠咳嗽次数，延长枸橼酸所致豚鼠咳嗽潜伏期，抑制组胺和乙酰胆碱溶液所致清醒豚鼠的实验性哮喘，拮抗磷酸组胺所致豚鼠气管平滑肌收缩，对抗豚鼠过敏性休克。
五指毛桃有明显的镇咳、平喘作用。
