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15年间发展中国家一所大学教学医院里儿童围手术期心脏骤停情况。

Perioperative cardiac arrests in children at a university teaching hospital of a developing country over 15 years.

作者信息

Ahmed Aliya, Ali Mohammad, Khan Mueenullah, Khan Fauzia

机构信息

Department of Anesthesia, Aga Khan University, Karachi, Pakistan.

出版信息

Paediatr Anaesth. 2009 Jun;19(6):581-6. doi: 10.1111/j.1460-9592.2009.02992.x.

Abstract

OBJECTIVE/AIM: To study the incidence, causes, and outcome of perioperative cardiac arrests in children at a university teaching hospital with an aim of improving quality of care.

BACKGROUND

Analysis of anesthesia-related complications is routinely performed by most anesthesia departments to make prevention strategies.

METHODS

All perioperative cardiac arrests in children up to 18 years from induction of anesthesia to postanesthesia care unit discharge or ICU admission during noncardiac surgery from January 1992 to December 2006 were analyzed. Outcome variable was noted as survival to discharge. Anesthesia-related cardiac arrests were identified and their causes analyzed.

RESULTS

Ten cardiac arrests occurred among 20216 patients. Overall incidence was 4.95 per 10000 (95% CI: 1.88-8.01). Six (6.53/10000) were females. Seven (19.44/10000) patients belonged to the classification III-IV of ASA physical status, eight (18.28/10000) were below 1 year, and two (1.26/10000) above 1 year. Three patients (6.53/10000) were undergoing emergency surgery. Anesthesia was primarily responsible in four cases. The causes of anesthesia-related arrests were medication-related (two), airway-related (one), and under-replacement of fluids (one). Seven patients died during the arrest and three were discharged home. The event was considered avoidable in seven (70%) cases.

CONCLUSION

Perioperative cardiac arrests were higher in patients with poor physical status, in those under 1 year of age, and in female patients. Anesthesia-related cardiac arrests were mainly due to medication- or airway-related causes. The majority of arrests were avoidable indicating the importance of prevention strategies.

摘要

目的

研究某大学教学医院儿童围手术期心脏骤停的发生率、原因及转归,以提高医疗质量。

背景

大多数麻醉科常规进行麻醉相关并发症分析以制定预防策略。

方法

分析1992年1月至2006年12月期间18岁以下儿童在非心脏手术中从麻醉诱导至麻醉后护理单元出院或入住重症监护病房期间发生的所有围手术期心脏骤停。转归变量记录为出院存活情况。确定与麻醉相关的心脏骤停并分析其原因。

结果

20216例患者中发生10例心脏骤停。总体发生率为每10000例中有4.95例(95%可信区间:1.88 - 8.01)。6例(每10000例中有6.53例)为女性。7例(每10000例中有19.44例)患者属于美国麻醉医师协会(ASA)身体状况分级III - IV级,8例(每10000例中有18.28例)年龄在1岁以下,2例(每10000例中有1.26例)年龄超过1岁。3例患者(每10000例中有6.53例)正在接受急诊手术。4例主要由麻醉导致。与麻醉相关的心脏骤停原因包括药物相关(2例)、气道相关(1例)和液体补充不足(1例)。7例患者在心脏骤停期间死亡,3例出院回家。7例(70%)事件被认为是可避免的。

结论

身体状况差的患者、1岁以下患者和女性患者围手术期心脏骤停发生率较高。与麻醉相关的心脏骤停主要由药物或气道相关原因引起。大多数心脏骤停是可避免的,这表明预防策略的重要性。

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