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大鼠发情周期中的卵巢人绒毛膜促性腺激素结合能力。

Ovarian HCG-binding capacity during the oestrous cycle of the rat.

作者信息

Siebers J W, Peters F, Engel W

出版信息

Acta Endocrinol (Copenh). 1977 Aug;85(4):850-4. doi: 10.1530/acta.0.0850850.

Abstract

Binding in 125I-labelled HCG to rat ovary varies during the oestrus cycle. The highest amount of binding was found in dioestrous-II rats (7.33 X 10(-15) mol of HCG per mg wet weight), while the lowest binding was observed in oestrous rats (1.67 X 10(-15) mol of HCG per mg wet weight) of circulation LH. It is concluded that the low binding capacity of the rat ovary in the oestrous stage is due to masking of the specific receptors by the excessively high LH hormone secretion in pro-oestrus.

摘要

125I标记的人绒毛膜促性腺激素(HCG)与大鼠卵巢的结合在发情周期中有所变化。在动情后期-II大鼠中发现结合量最高(每毫克湿重含7.33×10⁻¹⁵摩尔HCG),而在发情期大鼠中观察到结合量最低(每毫克湿重含1.67×10⁻¹⁵摩尔HCG),且循环中的促黄体生成素(LH)也是如此。得出的结论是,大鼠卵巢在发情期结合能力低是由于发情前期过高的LH激素分泌掩盖了特异性受体。

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