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伏尔加-乌拉尔人群的短串联重复序列(STR)数据库。

An STR database on the Volga-Ural population.

作者信息

Zhivotovsky Lev A, Akhmetova Vita L, Fedorova Sardana A, Zhirkova Victoria V, Khusnutdinova Elza K

机构信息

Institute of General Genetics, The Russian Academy of Sciences, Gubkin St. 3, Moscow 119991, Russia.

出版信息

Forensic Sci Int Genet. 2009 Sep;3(4):e133-6. doi: 10.1016/j.fsigen.2008.11.001. Epub 2008 Dec 23.

Abstract

This work develops a reference STR database on the Volga-Ural population, Russia, comprised of 640 individuals that were sampled from eight ethnic groups (Finno-Ugric Mari, Mordva-Moksha, Mordva-Erzja, Komi-Permjak, and Udmurt, and Turkic-speaking Bashkir, Tatar-Mishary, and Chuvash) and typed with 10 autosomal STR markers: TH01, CSF1P0, FGA, vWA, D3S1358, TPOX, D16S539, D8S1179, D13S317, FES. The groups differentiate in allele frequencies, and therefore we computed theta-values between allele frequencies in each ethnic groups and those in the database as a measure of their differentiation. Nevertheless, the Volga-Ural ethnic groups form a relatively compact cluster that greatly deviate from the Romanic Moldovans and the Turkic Yakuts, taken for comparison, and are closer to the Slavic Russians, Belarusians, and Ukrainians, although significantly differ from those as well.

摘要

这项工作建立了一个俄罗斯伏尔加-乌拉尔人群的STR参考数据库,该数据库由640名个体组成,这些个体来自八个族群(芬兰-乌戈尔语族的马里人、莫尔多瓦-莫克沙人、莫尔多瓦-叶尔扎人、科米-彼尔姆人、乌德穆尔特人,以及说突厥语的巴什基尔人、鞑靼-米沙里人、楚瓦什人),并使用10个常染色体STR标记进行分型:TH01、CSF1P0、FGA、vWA、D3S1358、TPOX、D16S539、D8S1179、D13S317、FES。这些族群在等位基因频率上存在差异,因此我们计算了每个族群与数据库中等位基因频率之间的θ值,作为衡量它们差异的指标。然而,伏尔加-乌拉尔族群形成了一个相对紧密的聚类,与作为比较对象的罗马尼亚摩尔多瓦人和突厥语族雅库特人大为不同,并且更接近斯拉夫语族的俄罗斯人、白俄罗斯人和乌克兰人,尽管与他们也有显著差异。

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