Murray M P, Pentland J L, Turnbull K, MacQuarrie S, Hill A T
Department of Respiratory Medicine, Royal Infirmary, University of Edinburgh, Edinburgh, UK.
Eur Respir J. 2009 Aug;34(2):361-4. doi: 10.1183/09031936.00163208.
This study explored the utility of sputum colour in clinically stable patients with bronchiectasis. Interpretation of sputum colour between the doctor and the patient was reliable (intraclass correlation coefficient 0.83 (95% confidence interval 0.76-0.89). Sputum colour predicted bacterial colonisation (5% in mucoid sputum; 43.5% in mucopurulent sputum; 86.4% in purulent sputum; p<0.0001). On multivariate logistic regression analysis, independent factors associated with purulent sputum were bacterial colonisation, varicose or cystic bronchiectasis, forced expiratory volume in 1 s <80% predicted and diagnosis of bronchiectasis aged <45 yrs.
本研究探讨了痰液颜色在临床稳定的支气管扩张症患者中的应用价值。医生与患者之间对痰液颜色的判断具有可靠性（组内相关系数为0.83（95%置信区间为0.76 - 0.89））。痰液颜色可预测细菌定植情况（黏液性痰液中为5%；黏液脓性痰液中为43.5%；脓性痰液中为86.4%；p<0.0001）。多因素逻辑回归分析显示，与脓性痰液相关的独立因素包括细菌定植、静脉曲张型或囊状支气管扩张、1秒用力呼气容积<预测值的80%以及45岁以下诊断为支气管扩张症。
