DeComas Amalia M, Heinrich Stephen D, Craver Randall
Department of Orthopaedic Surgery, Ochsner Health System, 1514 Jefferson Highway, New Orleans, LA 70121, USA.
J Pediatr Hematol Oncol. 2009 Jun;31(6):448-52. doi: 10.1097/MPH.0b013e3181a1c0c4.
The treatment of infantile fibrosarcoma has traditionally been wide resection. Chemotherapy has been investigated as an adjuvant and primary treatment in cases in which surgery would cause unacceptable morbidity. Recurrences normally occur within a year of completion of the chemotherapy and display the same histology. We present a child with an infantile fibrosarcoma of the elbow, successfully treated with chemotherapy alone, who developed a calcifying aponeurotic fibroma and a spindle cell/pleomorphic lipoma at the tumor site 12 years later.
婴儿纤维肉瘤的传统治疗方法是广泛切除。对于手术会导致不可接受的发病率的病例，已研究将化疗作为辅助治疗和主要治疗方法。复发通常发生在化疗完成后的一年内，且组织学表现相同。我们报告一名患有肘部婴儿纤维肉瘤的儿童，仅通过化疗成功治愈，12年后在肿瘤部位出现了钙化性腱膜纤维瘤和梭形细胞/多形性脂肪瘤。
