Department of Ophthalmology, Mamata Medical College Khammam, Andhra Pradesh, India.
Eye (Lond). 2010 Apr;24(4):608-12. doi: 10.1038/eye.2009.191. Epub 2009 Jul 24.
To compare short- and long-term IOP changes in small incision cataract surgery (SICS) vs conventional extracapsular cataract surgery (CECS).
A total of 232 eyes of as many patients undergoing cataract surgery were randomized to SICS or CECS. Sixteen eyes had to be excluded out of the study. IOP was recorded preoperatively and postoperatively on day 1, 2, and 7; and then after 1, 3, and 6 months. Only 160 eyes remained under 6-month follow-up, out of which 48 had CECS and remaining 112, SICS. Results were analysed statistically (repeated measure ANOVA, multiple comparisons).
A significantly higher IOP was observed on day 1, 2, and 7 in both types of surgeries as compared to mean preoperative IOP. Variation in rise was more pronounced in CECS (nearly twofold) than in SICS (P<0.05). Maximum decrease in IOP occurred during the first week and it was more rapid in SICS than CECS. At 3 months, IOP was significantly higher than baseline in CECS but significantly lower in SICS. From 3 to 6 months, there was no further decrease in IOP in either type of surgery.
IOP rises significantly on day one in CECS and SICS and thereafter comes down slightly by day 2 and rapidly by day 7. IOP rise is more pronounced in CECS than in SICS. After 1 week to 3 months, IOP decline is very gradual and thereafter ceases to decrease.
比较小切口白内障手术（SICS）与传统囊外白内障手术（CECS）的短期和长期眼压变化。
共有 232 只接受白内障手术的眼随机分为 SICS 或 CECS 组。有 16 只眼因各种原因被排除在研究之外。术前和术后第 1、2、7 天，以及术后第 1、3、6 个月记录眼压。在 6 个月的随访中，只有 160 只眼保留下来，其中 48 只眼接受了 CECS，112 只眼接受了 SICS。结果采用重复测量方差分析（ANOVA）和多重比较进行统计学分析。
与术前平均眼压相比，两种手术类型在术后第 1、2、7 天的眼压均显著升高。CECS 的眼压升高幅度（近两倍）明显大于 SICS（P<0.05）。眼压最大降幅发生在第 1 周，SICS 比 CECS 更快。术后 3 个月，CECS 的眼压明显高于基线，但 SICS 的眼压明显低于基线。从术后 3 个月到 6 个月，两种手术类型的眼压均无进一步下降。
CECS 和 SICS 术后第 1 天眼压显著升高，此后第 2 天和第 7 天略有下降。CECS 的眼压升高幅度大于 SICS。术后第 1 周至第 3 个月，眼压下降非常缓慢，此后停止下降。
