巴西弗洛里亚诺波利斯甲状腺癌发病率上升：2000年与2005年确诊病例的对比研究
Increase incidence of thyroid cancer in Florianopolis, Brazil: comparative study of diagnosed cases in 2000 and 2005.
作者信息
Cordioli Maria Isabel C V, Canalli Maria Heloísa B S, Coral Marisa Helena C
机构信息
Serviço de Endocrinologia, Hospital Universitário, Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil.
出版信息
Arq Bras Endocrinol Metabol. 2009 Jun;53(4):453-60. doi: 10.1590/s0004-27302009000400011.
OBJECTIVE
To provide epidemiological information about thyroid cancer (TC) in the Metropolitan area of Florianopolis and investigate some factors that could be associated with this type of cancer.
METHOD
This study analyzed data of patients who had TC diagnosed and underwent surgical treatment in 2000 and 2005. Epidemiological factors about patients, tumors and surgical procedures were evaluated.
RESULTS
In 2000 and 2005, an increasing incidence of TC at a rate of 132.33% was detected. The increased rate was mainly observed for tumors measuring less than 1 cm (p = 0.004). Results also showed an increase in the number of multifocal tumors (p = 0.02) and in the rate of total thyroidectomy (p = 0.002).
CONCLUSIONS
The increasing incidence of TC in the Metropolitan area of Florianopolis is probably due to more invasive thyroid nodule management. Future studies are necessary to establish potential predicting factors for papillary thyroid microcarcinoma aggressiveness, as well as predictors of follicular lesion malignancy to identifying more accurately the appropriate therapy approach.
目的
提供弗洛里亚诺波利斯大都市区甲状腺癌（TC）的流行病学信息，并调查可能与这种癌症相关的一些因素。
方法
本研究分析了2000年和2005年被诊断为TC并接受手术治疗的患者的数据。评估了患者、肿瘤和手术程序的流行病学因素。
结果
在2000年和2005年，检测到TC发病率以132.33%的速度上升。发病率增加主要见于直径小于1厘米的肿瘤（p = 0.004）。结果还显示多灶性肿瘤数量增加（p = 0.02）以及甲状腺全切率上升（p = 0.002）。
结论
弗洛里亚诺波利斯大都市区TC发病率上升可能归因于对甲状腺结节更积极的处理方式。未来有必要开展研究以确定甲状腺微小乳头状癌侵袭性的潜在预测因素，以及滤泡性病变恶性程度的预测指标，从而更准确地确定合适的治疗方法。
Zotero 插件