Suppr超能文献

社区药剂师在患者出院时进行用药评估和患者咨询。

Medication review and patient counselling at discharge from the hospital by community pharmacists.

作者信息

Hugtenburg J G, Borgsteede S D, Beckeringh J J

机构信息

Department of Clinical Pharmacology and Pharmacy, VU University Medical Center, Amsterdam, The Netherlands.

出版信息

Pharm World Sci. 2009 Dec;31(6):630-7. doi: 10.1007/s11096-009-9314-z. Epub 2009 Aug 1.

Abstract

AIMS

In 2001, the Association of Amsterdam Community Pharmacists adopted a programme to improve the pharmaceutical care of patients who were discharged from hospital with five or more drug prescriptions. A comprehensive protocol for pharmaceutical care at discharge (IBOM-1) was developed. The aim of the study was to evaluate the initial IBOM protocol and to study the effects of the protocol on drug therapy and patient satisfaction as well as on drug use compliance and mortality.

METHOD

A controlled intervention study involving 37 community pharmacies and 715 of their registered patients who were discharged from a hospital and using at least five prescribed drugs in the years 2001-2003. The intervention included an extensive medication review and drug counselling at the patient's home.

MAIN OUTCOME MEASURE

Pharmacy intervention activities, changes in medication, discontinuation of drugs prescribed at discharge, mortality, time spent on the intervention activities, and medication cost savings were all evaluated. Patient satisfaction was measured by means of a questionnaire.

RESULTS

379 and 336 patients were enrolled in the intervention and control groups, respectively. The mean number of drugs per patient not dispensed, concomitantly dispensed, or of which the quantity was changed was higher in the intervention group than in the control group (0.70 +/- 1.74 vs. 0.40 +/- 1.43, 0.11 +/- 0.40 vs. 0.038 +/- 0.26, and 0.29 +/- 1.05 vs. 0.097 +/- 0.52, respectively). The mean number of drugs for which the dose or dosage form was changed was similar in both groups. Substitution of brand for generic or vice versa was greater in the intervention group. Changes resulting from a PAIS signal were similar in both groups. The mean number of drugs per patient for which contact was required with the physician or the Pharmacy Hospital Service Desk was higher in the intervention group (0.35 +/- 0.51 vs. 0.16 +/- 0.38). About 40% of home visits resulted in the clearing of redundant drug supplies. The IBOM-1 intervention did not influence discontinuation of drugs prescribed at discharge, nor did it influence mortality. Medication costs were slightly reduced. More patients of intervention pharmacies than of control pharmacies indicated that they were (very) satisfied with the drug counselling by their community pharmacist upon delivery of their discharge medication (87% vs. 50%; chi(2) < 0.001).

CONCLUSIONS

Structured pharmaceutical care according to the IBOM-1 protocol led to more changes in drug therapy. Home visits resulted in the clearing of redundant home drug supplies. In addition, patients were highly satisfied with the counselling at discharge from hospital by their community pharmacist. Patient counselling at discharge from hospital by pharmacists, therefore, appears to be a meaningful pharmaceutical care activity.

摘要

目的

2001年,阿姆斯特丹社区药剂师协会采用了一项计划,以改善出院时携带五种或更多药物处方的患者的药学服务。制定了一份出院时药学服务的综合方案(IBOM - 1)。本研究的目的是评估初始的IBOM方案,并研究该方案对药物治疗、患者满意度以及用药依从性和死亡率的影响。

方法

一项对照干预研究,涉及37家社区药房及其715名在2001 - 2003年期间出院且使用至少五种处方药的注册患者。干预措施包括在患者家中进行广泛的用药审查和药物咨询。

主要观察指标

评估药房干预活动、用药变化、出院时所开药物的停用情况、死亡率、干预活动所花费的时间以及用药成本节省情况。通过问卷调查来衡量患者满意度。

结果

干预组和对照组分别纳入了379名和336名患者。干预组中每位患者未配发、同时配发或数量改变的药物平均数量高于对照组(分别为0.70±1.74 vs. 0.40±1.43、0.11±0.40 vs. 0.038±0.26以及0.29±1.05 vs. 0.097±0.52)。两组中剂量或剂型改变的药物平均数量相似。干预组中品牌药与非专利药的替换或反之情况更多。由药物不良反应信号引发的变化在两组中相似。干预组中每位患者需要与医生或药房医院服务台联系的药物平均数量更高(0.35±0.51 vs. 0.16±0.38)。约40%的家访导致多余药品储备被清理。IBOM - 1干预并未影响出院时所开药物的停用情况,也未影响死亡率。用药成本略有降低。与对照药房的患者相比,干预药房的更多患者表示他们对社区药剂师在出院用药时提供的药物咨询(非常)满意(87% vs. 50%;卡方检验P < 0.001)。

结论

根据IBOM - 1方案进行的结构化药学服务导致了更多的药物治疗变化。家访导致多余的家庭药品储备被清理。此外,患者对社区药剂师在出院时提供的咨询高度满意。因此,药剂师在出院时为患者提供咨询似乎是一项有意义的药学服务活动。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验