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生育患者及其处方:对一家生殖内分泌诊所患者与药剂师互动情况的两年审计。

Fertility patients and their prescriptions: a two-year audit of patient-pharmacist interactions in a reproductive endocrinology practice.

作者信息

Sills Eric Scott, Shurpyak Serhiy A, Gorman Deirdre J, Shkrobot Lyuda V, Murray Grainne U, O'Connor Beppi Mg, Rapple Una E, Fogarty Alicia O, Sarkova Pavlina, Brickell Kathy M, Walsh David J

机构信息

The Sims Institute and Sims International Fertility Clinic, Dublin, Ireland.

出版信息

Int Arch Med. 2009 Aug 3;2(1):24. doi: 10.1186/1755-7682-2-24.

Abstract

BACKGROUND

This study assessed pharmacy performance and satisfaction as reported by patients during ovulation induction therapy.

MATERIALS AND METHODS

Patients (n = 1269) receiving gonadotropin prescriptions for intrauterine insemination or in vitro fertilisation-embryo transfer in 2007-2008 were prospectively interviewed by nurses and/or completed a structured questionnaire to evaluate pharmacy performance. "Community" (n = 12) and "specialty" (n = 2) pharmacy status (C vs. S) was defined by each pharmacy, and all pharmacies were selected by patients before cycle start. Patient comments about their pharmacy were classified into five types: i) Dispensing error-gonadotropin, ii) Dispensing error-non gonadotropin, iii) Mistake in prescribed medical equipment/supplies, iv) Counselling/communication inaccuracy, and v) Inventory problem or other.

RESULTS

391 pharmacy concerns were reported from 150 fertility patients during the study period. The majority (75.9%) of patients selected a S pharmacy to fill their prescriptions, and this pharmacy type was identified in 2.8% of adverse pharmacy encounters (p < 0.0001). Non-gonadotropin prescriptions filled at C pharmacies accounted for 40.2% of all complaints, followed by problems with prescriptions for supplies (20.2%) and gonadotropins (18.7%) at C pharmacies. Patient conflict involving S pharmacies was limited (n = 11), and related to operating hours and medication delivery logistics.

CONCLUSION

Fertility patients reported a disproportionate and significantly higher number of adverse pharmacy encounters from C pharmacies compared to S pharmacies. Although no licensing mechanism in Ireland currently recognises special training or certification in any area of pharmacy practice, informal self-designations by pharmacies remain a useful discriminator. Level of familiarity with fertility medicines and availability of inventory are important characteristics to be considered when counselling fertility patients about pharmacy choice. Those who select a C pharmacy should be advised to allow extra time for inventory verification, order confirmation, and additional counselling. Additional study is needed to determine if a minimum volume of fertility-related prescriptions is necessary to assure competence in this particular field of pharmacy practice.

摘要

背景

本研究评估了患者在排卵诱导治疗期间报告的药房表现及满意度。

材料与方法

对2007年至2008年接受促性腺激素处方用于宫内授精或体外受精 - 胚胎移植的患者(n = 1269),由护士进行前瞻性访谈和/或让患者填写结构化问卷以评估药房表现。各药房自行定义“社区”(n = 12)和“专科”(n = 2)药房状态(C与S),且所有药房均由患者在周期开始前选定。患者对其药房的评价分为五类:i)促性腺激素配药错误,ii)非促性腺激素配药错误,iii)处方医疗设备/用品错误,iv)咨询/沟通不准确,v)库存问题或其他。

结果

在研究期间,150名生育患者报告了391起药房相关问题。大多数(75.9%)患者选择S药房配药,且该药房类型在2.8%的不良药房事件中被发现(p < 0.0001)。C药房配药的非促性腺激素处方占所有投诉的40.2%,其次是C药房的用品处方问题(20.2%)和促性腺激素问题(18.7%)。涉及S药房的患者冲突有限(n = 11),且与营业时间和药物配送物流有关。

结论

与S药房相比,生育患者报告的C药房不良药房事件数量不成比例且显著更高。尽管爱尔兰目前没有许可机制认可药房实践任何领域的特殊培训或认证,但药房的非正式自我认定仍是一个有用的区分方式。在为生育患者提供药房选择咨询时应考虑对生育药物的熟悉程度和库存可用性等重要特征。应建议选择C药房的患者预留额外时间用于库存核实、订单确认和额外咨询。需要进一步研究以确定是否需要最低数量的生育相关处方来确保在这一特定药房实践领域的能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6276/2727501/07b39f75300c/1755-7682-2-24-1.jpg

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