一些禽腺病毒分离株表现出广泛的抗原性。
Broad antigenicity exhibited by some isolates of avian adenovirus.
作者信息
Cowen B, Calnek B W, Hitchner S B
出版信息
Am J Vet Res. 1977 Jul;38(7):559-62.
Ten of 16 isolates of avian adenovirus could be readily classified as members of serotypes 2, 5, or 7. However, 6 exhibited broad neutralization reactions which created typing problems. Detailed studies of these interactions revealed that our prototype for serotype 5 (i.e., T-8; subsequently found to be an "intermediate" strain) contributed to this broad cross-reactivity because it shared antigens with members of serotypes 5 and 7. As a result of this study, TR-59 or 58-1 is recommended as the suitable prototype for the serotype 5 viruses. The 6 broadly reactive isolates were classified as serologic "variants" of serotypes 5 and 7.
16株禽腺病毒分离株中有10株可轻易归类为2型、5型或7型血清型的成员。然而，有6株表现出广泛的中和反应，这造成了分型问题。对这些相互作用的详细研究表明，我们的5型血清型原型（即T-8；随后发现是一种“中间”毒株）导致了这种广泛的交叉反应，因为它与5型和7型血清型的成员共享抗原。这项研究的结果是，推荐TR-59或58-1作为5型病毒的合适原型。这6株具有广泛反应性的分离株被归类为5型和7型血清型的血清学“变体”。
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