[Study of the changes in carbohydrate metabolism as a diagnostic test of acute hypothalamic syndrome in severe cranio-cerebral trauma].

A total of 66 patients who suffered a severe isolated or concomitant craniocerebral injury were examined. Additionally, a study was made of some indicators of carbohydrate metabolism in the general circulatory bed, acid-base state of the arterialized blood, partial oxygen tension and hemoglobin saturation with arterial blood oxygen. In 10 patients, the same indicators were compared to EEG alterations and the pulse constituent of the finger photoplethysmogram. It was revealed that alterations in carbohydrate metabolism in the form of lactic acidosis and anaerobiosis developed not only because of hemodynamic and ventilatory disorders. Analogous alterations were also seen in the course of the development of the acute hypothalamic syndrome (AHS) with the lack of ventilatory and hemodynamic disorders. The above disorders of carbohydrate metabolism may serve as one of the early diagnostic tests of AHS development and be used for the control over the treatment efficacy and prediction.