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器官获取组织中协议驱动变革后器官获取量的逐步增加:一项为期15年的评估。

Incremental increases in organ retrieval after protocol driven change in an organ procurement organization: a 15-year assessment.

作者信息

Franklin Glen A, Smith Jason W, Daugherty Wendy, Threkeld Tom, Garrison R Neal

机构信息

Department of Surgery, 2nd Floor ACB, 550 South Jackson Street, University of Louisville, Louisville, KY 40292, USA.

出版信息

Am Surg. 2009 Jul;75(7):537-43; discussion 543-4. doi: 10.1177/000313480907500702.

Abstract

The need for transplantable organs exceeds the available supply. Organ procurement organizations (OPOs) have undergone both voluntary and mandated changes to optimize available organs. The data from a single statewide OPO was reviewed from 1993 to 2008 and tracked with implementation of new protocols. During the study, 5548 organs were recovered with 4875 transplanted from 1441 donors (3.38 organs transplanted/donor (OTPD)). The conversion rate (CR) for consent rose from 42 to 72 per cent whereas the average age of donors increased from 33 to 45 years. After implementation of a family support liaison program, a higher performing hospital in the OPO realized an increase in CR from 57 to 97 per cent over 8 years. Implementation of an intensivist program improved OTPD. The number of standard criteria donors and extended criteria donors (ECD) increased. The increase in standard criteria donors yielded a large number of thoracic organs. ECD increased as did the organ discard rate from 8 to 16 per cent. Increases in organ retrieval were noted after incremental changes in OPO protocol. Family support and intensivist programs enhanced CR and OTPD. Increases in the number of ECD were noted with increasing age after the introduction of the intensivist program and an increase in transplant center use of these organs.

摘要

可移植器官的需求超过了现有供应。器官获取组织(OPO)已经历了自愿和强制的变革,以优化可用器官。对一个单一州级OPO从1993年到2008年的数据进行了审查,并随着新方案的实施进行跟踪。在研究期间,从1441名捐赠者身上获取了5548个器官,其中4875个器官被移植(移植器官/捐赠者(OTPD)为3.38个)。同意转化率(CR)从42%上升到72%,而捐赠者的平均年龄从33岁增加到45岁。在实施家庭支持联络计划后,OPO中一家表现较好的医院在8年时间里将CR从57%提高到了97%。实施强化治疗计划提高了OTPD。标准标准捐赠者和扩展标准捐赠者(ECD)的数量增加了。标准标准捐赠者数量的增加产生了大量的胸腔器官。ECD增加了,器官丢弃率也从8%增加到了16%。在OPO方案逐步改变后,器官获取量有所增加。家庭支持和强化治疗计划提高了CR和OTPD。在引入强化治疗计划后,随着年龄的增长,ECD的数量增加,移植中心对这些器官的使用也增加了。

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