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提高一级创伤中心的供体转化率:最佳实践指南的影响

Improving Donor Conversion Rates at a Level One Trauma Center: Impact of Best Practice Guidelines.

作者信息

Alban Rodrigo F, Gibbons Bobby L, Bershad Vanessa L

机构信息

Surgical Critical Care, Cedars-Sinai Medical Center.

Department of Surgical Education, Orlando Regional Medical Center.

出版信息

Cureus. 2016 Nov 22;8(11):e891. doi: 10.7759/cureus.891.

Abstract

BACKGROUND

Organ availability is a consistently limiting factor in transplant surgery. A primary driver of this limitation is donor conversion rate, which is defined as the percentage of eligible donors for whom procurement is actually performed. An alternative way to increase organ availability is through improved utilization of organs from donors after cardiac death (DCD). Recently, a concerted, multidisciplinary effort has been made within our system to improve conversion rates and DCD utilization, thus increasing organ availability.

STUDY DESIGN

Retrospective analysis of a prospectively collected database from TransLife, our local organ procurement organization (OPO), as well as the Orlando Regional Medical Center (ORMC) trauma registry, from 2009-2012 (up to 2013 for DCD). During which time, this organization implemented best practice guidelines to improve conversions and DCD utilization. We analyzed yearly conversion rates, DCD donations and population demographics before and after implementation of these policies.

RESULTS

During the study period, donor conversion rates significantly improved from 58% in 2009 to 82% percent in 2012 hospital-wide (P<0.05); and from 50% in 2009 to 81% in 2012 among trauma patients alone (P<0.05). In addition, total organs transplanted increased from 13 to 31 organs (P<0.05) after implementation of best practice guidelines. No significant differences in trauma population demographics were noted during the study period.

CONCLUSIONS

Based on our experience, the establishment of best practice policies for referral of potential donors, coupled with programs to educate hospital staff on the existence and importance of these policies, leads to significant improvement in donor conversion rates and increased utilization of DCD donors.

摘要

背景

器官供应一直是移植手术中的限制因素。造成这种限制的一个主要因素是供体转化率,其定义为实际进行器官获取的合格供体的百分比。增加器官供应的另一种方法是提高对心脏死亡后供体(DCD)器官的利用率。最近,我们的系统内进行了协同的多学科努力,以提高转化率和DCD利用率,从而增加器官供应。

研究设计

对来自我们当地器官获取组织(OPO)TransLife以及奥兰多地区医疗中心(ORMC)创伤登记处2009年至2012年(DCD数据截至2013年)前瞻性收集的数据库进行回顾性分析。在此期间,该组织实施了最佳实践指南以提高转化率和DCD利用率。我们分析了这些政策实施前后的年度转化率、DCD捐赠情况和人口统计学特征。

结果

在研究期间,全院供体转化率从2009年的58%显著提高到2012年的82%(P<0.05);仅创伤患者的供体转化率从2009年的50%提高到2012年的81%(P<0.05)。此外,实施最佳实践指南后,移植的器官总数从13个增加到31个(P<0.05)。研究期间创伤患者的人口统计学特征没有显著差异。

结论

根据我们的经验,建立潜在供体转诊的最佳实践政策,再加上向医院工作人员宣传这些政策的存在及其重要性的项目,可显著提高供体转化率,并增加DCD供体的利用率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7723/5178983/34408c0ef84d/cureus-0008-00000000891-i01.jpg

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