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[流感和副流感住院患者慢性病急性加重的发生率]

[The incidence of exacerbations in chronic diseases in patients hospitalized with influenza and para-influenza].

作者信息

Bondarenko S S, Tumanov F A

出版信息

Ter Arkh. 1990;62(11):39-42.

PMID:1965617
Abstract

A retrospective analysis was made of the case reports of 829 patients admitted to the infectious department with a diagnosis of influenza (592) and parainfluenza (237). In all the patients, the diagnosis was supported serologically with the aid of the hemagglutination inhibition test, with the antibody titer in the serum rising 4-fold and more. In part of the patients the indicated test was used in combination with the immunofluorescence test in studying nasopharyngeal smears, whereas in part of the patients, it was coupled with virological tests. It has been revealed that in addition to the most frequently occurring complications on the part of the bronchopulmonary system and ENT organs caused by the pneumococcal and streptococcal flora, there were complications on the part of the endocrine, urogenital, nervous and gastrointestinal systems, equally in patients with influenza and parainfluenza. In patients with postinfarction cardiosclerosis, influenza B and mixed influenza run the most unfavourable course, provoking deterioration of coronary heart disease in every other patient. In 66.6% of cases, exacerbation of coronary heart disease fell within the period of early convalescence of patients with influenza and parainfluenza.

摘要

对收治于感染科的829例诊断为流感(592例)和副流感(237例)的病例报告进行了回顾性分析。所有患者均通过血凝抑制试验进行血清学诊断支持,血清抗体滴度升高4倍及以上。部分患者在研究鼻咽涂片时,上述试验与免疫荧光试验联合使用,而部分患者则与病毒学试验联合使用。结果显示,除了由肺炎球菌和链球菌菌群引起的支气管肺系统和耳鼻喉器官最常见的并发症外,内分泌、泌尿生殖、神经和胃肠道系统也出现了并发症,流感和副流感患者均如此。在心肌梗死后心硬化患者中,乙型流感和混合型流感病情最不利,每两名患者中就有一名冠心病病情恶化。在66.6%的病例中,冠心病加重发生在流感和副流感患者的早期康复期。

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