[铅中毒时神经系统的形态学变化。I. 实验性诱导的铅中毒性神经病]
[Morphological changes in the nervous system in lead poisoning. I. Experimentally induced lead neuropathy].
作者信息
Ivanova A, Nachev S
出版信息
Eksp Med Morfol. 1990;29(4):18-23.
PMID:1965890
Abstract
A morphological study on experimental model of lead (Pb) neuropathy (by the method of Pentschev, A., 1966) was described. Dense inclusions in Schwann's cells and satellite cells of the sensory ganglia were found by an electron microscope in the examined peripheral nerves (n. ischiadicus) and sensory ganglia (g. lumbale and g. trigeminale--Gasseri). These finding supported direct toxic action of Pb on these structures and proved their participation in the pathogenesis of developing neuropathy.
摘要
本文描述了铅（Pb）神经病变实验模型的形态学研究（采用A. Pentschev 1966年的方法）。通过电子显微镜在检查的周围神经（坐骨神经）和感觉神经节（腰神经节和三叉神经节——加塞神经节）中发现了施万细胞和感觉神经节卫星细胞中的致密包涵体。这些发现支持了铅对这些结构的直接毒性作用，并证明它们参与了神经病变发展的发病机制。
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