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放射性骨坏死风险患者的管理:英国牙医及口腔颌面外科科室的调查结果及最佳实践建议

Management of patients at risk of osteoradionecrosis: results of survey of dentists and oral & maxillofacial surgery units in the United Kingdom, and suggestions for best practice.

作者信息

McLeod Niall M H, Bater Michael C, Brennan Peter A

机构信息

Department of Oral & Maxillofacial Surgery, Queen Alexandra Hospital, Portsmouth, UK. niall

出版信息

Br J Oral Maxillofac Surg. 2010 Jun;48(4):301-4. doi: 10.1016/j.bjoms.2009.06.128. Epub 2009 Aug 5.

DOI:10.1016/j.bjoms.2009.06.128
PMID:19660845
Abstract

We aimed to find out whether dental practitioners take specific measures to identify patients who are at risk of osteoradionecrosis (ORN) of the jawbones; how oral and maxillofacial surgery units in the United Kingdom manage patients who have had radiotherapy and require dental extractions, and the evidence behind current practice. We sent postal questionnaires to 60 dentists and 117 maxillofacial units. Dentists were questioned about measures used to identify radiotherapy patients, and use of antibiotic prophylaxis. Maxillofacial units were questioned about the existence of written protocols and the measures used to minimise the risk of ORN. Thirty-five percent of dentists questioned ask specifically about head and neck cancer or radiotherapy as part of their medical history, and 5% of maxillofacial units questioned had written protocols for the management of patients who had had radiotherapy or had previously been diagnosed with ORN. Prophylactic antibiotics are recommended for patients at risk of ORN by 16% of dentists and 81% of maxillofacial units. Preoperative mouthwash is recommended by 59% of maxillofacial units. Identification of patients at risk of ORN is the first step in prevention but it is not done efficiently at present. Recommendations include the use of preoperative mouthwash and prophylactic antibiotics. Operations should be atraumatic and should be done by experienced clinicians.

摘要

我们旨在查明牙科医生是否采取特定措施来识别有颌骨放射性骨坏死(ORN)风险的患者;英国的口腔颌面外科科室如何管理接受过放疗且需要拔牙的患者,以及当前做法背后的依据。我们向60名牙医和117个颌面外科科室邮寄了调查问卷。询问了牙医用于识别放疗患者的措施以及抗生素预防的使用情况。询问了颌面外科科室关于书面方案的存在情况以及用于将ORN风险降至最低的措施。35%接受询问的牙医在病史询问中会特别询问头颈癌或放疗情况,5%接受询问的颌面外科科室有针对接受过放疗或先前被诊断为ORN的患者的管理书面方案。16%的牙医和81%的颌面外科科室建议对有ORN风险的患者使用预防性抗生素。59%的颌面外科科室建议术前使用漱口水。识别有ORN风险的患者是预防的第一步,但目前这一步做得并不高效。建议包括使用术前漱口水和预防性抗生素。手术应无创,且应由经验丰富的临床医生进行。

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