Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Wisconsin Medical School, Madison, Wisconsin 53792-7375, USA.
J Voice. 2010 May;24(3):260-9. doi: 10.1016/j.jvoice.2008.09.005. Epub 2009 Aug 5.
The human vocal fold is treated as a continuous, transversally isotropic, porous solid saturated with liquid. A set of mathematical equations, based on the theory of fluid-saturated porous solids, is developed to formulate the vibration of the vocal fold tissue. As the fluid-saturated porous tissue model degenerates to the continuous elastic tissue model when the relative movement of liquid in the porous tissue is ignored, it can be considered a more general description of vocal fold tissue than the continuous, elastic model. Using the fluid-saturated porous tissue model, the vibration of a bunch of one-dimensional fibers in the vocal fold is analytically solved based on the small-amplitude assumption. It is found that the vibration of the tissue will lead to the accumulation of excess liquid in the midmembranous vocal fold. The degree of liquid accumulation is positively proportional to the vibratory amplitude and frequency. The correspondence between the liquid distribution predicted by the porous tissue theory and the location of vocal nodules observed in clinical practice, provides theoretical evidence for the liquid accumulation hypothesis of vocal nodule formation (Jiang, Ph.D., dissertation, 1991, University of Iowa).
人声带被视为充满液体的连续、横向各向同性、多孔固体。建立了一组基于流固两相多孔固体理论的数学方程来描述声带组织的振动。由于当忽略多孔组织中液体的相对运动时，流体饱和多孔组织模型退化到连续弹性组织模型，因此它可以被认为是比连续弹性模型更一般的声带组织描述。利用流体饱和多孔组织模型，基于小振幅假设，对声带中一束一维纤维的振动进行了分析求解。研究发现，组织的振动会导致中膜声带中多余液体的积聚。液体积累的程度与振动幅度和频率成正比。多孔组织理论预测的液体分布与临床观察到的声带小结位置之间的对应关系，为声带小结形成的液体积累假说提供了理论依据（Jiang，博士论文，1991 年，爱荷华大学）。
