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[作为控制输尿管自发活动因素的膜电位]

[The membrane potential as the factor controlling the spontaneous activity of the ureter].

作者信息

Kazarian K V, Tiraian A S, Akopian R R

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1990 Oct;76(10):1458-64.

PMID:1966102
Abstract

The spontaneous activity of various zones of the guinea pig ureter was studied by means of "sucrose gap" technique. Two of these zones, perirenal and pericystic ones are pacemakers. An increase in the K+ ions amount in the medium, electric stimulation and administration of acetylcholine, histamine or noradrenaline induced rhythmic spikes in initially inactive middle regions of the ureter. At the same time, they reduced or blocked the activity of the pacemaker zones. The existence of the MP gradient along the ureter from the ends to its central regions, is discussed.

摘要

采用“蔗糖间隙”技术研究了豚鼠输尿管各区域的自发活动。其中两个区域,即肾周区和膀胱周区是起搏点。培养基中钾离子含量增加、电刺激以及给予乙酰胆碱、组胺或去甲肾上腺素可在输尿管最初无活性的中间区域诱发节律性峰电位。同时,它们降低或阻断了起搏点区域的活动。文中讨论了沿输尿管从两端到其中心区域存在跨膜电位梯度的情况。

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