Örnek Kemal, Özdemir Mehmet, Ergin Ahmet
Department of Ophthalmology, School of Medicine, Kirikkale University, Kirikkale, Turkey.
J Med Microbiol. 2009 Nov;58(Pt 11):1517-1518. doi: 10.1099/jmm.0.011197-0. Epub 2009 Aug 6.
Keratitis with endophthalmitis of the right eye occurred in a 78-year-female following a complicated cataract surgery. Prompt intravitreal vancomycin and ceftazidime with topical fortified tobramycin and cefazolin treatments were started. The corneal, aqueous and vitreous cultures grew a Burkholderia cepacia complex (Bcc) strain on the fourth day. Restriction fragment length polymorphism analysis of the recA amplicon revealed B. cepacia genomovar I. The organism was found to be susceptible to ceftazidime, ciprofloxacin and ofloxacin. Topical ciprofloxacin was given immediately. At day 10, the pain relieved and the clinical condition of the patient improved with resolution of the purulent discharge, severe circumcorneal congestion and chemosis. The size of the corneal abscess and anterior chamber exudation decreased. The Bcc should be included among the bacterial species that may cause keratitis following intraocular surgeries.
一名78岁女性在复杂白内障手术后发生右眼角膜炎并伴有眼内炎。随即开始玻璃体内注射万古霉素和头孢他啶，并局部使用强化妥布霉素和头孢唑林进行治疗。角膜、房水和玻璃体培养物在第4天培养出一株洋葱伯克霍尔德菌复合体（Bcc）菌株。recA扩增子的限制性片段长度多态性分析显示为洋葱伯克霍尔德菌基因I型。发现该菌株对头孢他啶、环丙沙星和氧氟沙星敏感。立即给予局部环丙沙星治疗。在第10天，疼痛缓解，患者的临床状况改善，脓性分泌物、严重角膜周围充血和球结膜水肿消退。角膜脓肿和前房渗出物的大小减小。Bcc应被列入可能导致眼内手术后角膜炎的细菌种类之中。
