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Trophoblastic tumour, oral contraceptive therapy and pregnancy associated alpha2-glycoprotein (PAAG), case report.

作者信息

Teisner B, Mogensen B, Folkersen J, Svehag S E

出版信息

Br J Obstet Gynaecol. 1977 Aug;84(8):630-2. doi: 10.1111/j.1471-0528.1977.tb12667.x.

DOI:10.1111/j.1471-0528.1977.tb12667.x
PMID:196614
Abstract

Pregnancy associated alpha2-glycoprotein (PAAG) and human chorionic gonadotrophin (HCG) levels were studied in a patient with an invasive mole who was being treated with cytotoxic drugs and oral contraceptives. Both the PAAG and HCG levels fell during cytotoxic drug treatment while oral contraceptives caused a rise in PAAG concentrations. A relation between oestrogen-induced PAAG and prolonged survival of trophoblastic tumour is proposed.

摘要

相似文献

1
Trophoblastic tumour, oral contraceptive therapy and pregnancy associated alpha2-glycoprotein (PAAG), case report.
Br J Obstet Gynaecol. 1977 Aug;84(8):630-2. doi: 10.1111/j.1471-0528.1977.tb12667.x.
2
Relationship of oral contraception to development of trophoblastic tumour after evacuation of a hydatidiform mole.葡萄胎清宫术后口服避孕药与滋养细胞肿瘤发生的关系。
Br J Obstet Gynaecol. 1976 Dec;83(12):913-6. doi: 10.1111/j.1471-0528.1976.tb00774.x.
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Pregnancy beta1 glycoprotein and chorionic gonadotrophin in the serum of patients with trophoblastic and non-trophoblastic tumours.
Eur J Cancer (1965). 1978 Dec;14(12):1331-5. doi: 10.1016/0014-2964(78)90114-7.
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Utility of assay of alpha subunit of human chorionic gonadotropin in management of gestational, trophoblastic malignancies.人绒毛膜促性腺激素α亚基检测在妊娠滋养细胞肿瘤管理中的应用
Am J Obstet Gynecol. 1980 Nov 1;138(5):545-9. doi: 10.1016/0002-9378(80)90284-7.
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Circulating placental proteins (hCG, SP1 and PP5) in trophoblastic disease.
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6
[Clinical significance of pregnancy-specific beta glycoprotein, human placental lactogen and beta-human chorionic gonadotropin in the serum of patients with trophoblastic diseases].[妊娠特异性β-糖蛋白、人胎盘催乳素及β-人绒毛膜促性腺激素在滋养细胞疾病患者血清中的临床意义]
Zhonghua Yi Xue Za Zhi. 1989 Apr;69(4):206-8, 16.
7
Early detection of persistent trophoblastic tumour by serum human chorionic gonadotrophin monitoring after molar pregnancy.葡萄胎妊娠后通过血清人绒毛膜促性腺激素监测早期发现持续性滋养细胞肿瘤
Chin Med J (Engl). 1999 Mar;112(3):260-3.
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[The serum concentration of specific beta 1-glycoprotein in trophoblastic disease].[滋养层疾病中特异性β1-糖蛋白的血清浓度]
Akush Ginekol (Sofiia). 1989;28(2):15-9.
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Treatment of nonmetastatic gestational trophoblastic disease with sequential intramuscular and oral methotrexate.
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Diagnostic reliability of simultaneous measurements of beta human chorionic gonadotropin and pregnancy-specific beta-1-glycoprotein in serum of patients with trophoblastic disease.
Gynecol Obstet Invest. 1987;23(3):151-6. doi: 10.1159/000298854.

引用本文的文献

1
The pregnancy-associated alpha 2-glycoprotein (alpha 2-PAG). A tumour marker?妊娠相关α2-糖蛋白(α2-PAG)。一种肿瘤标志物?
Klin Wochenschr. 1981 Feb 16;59(4):149-55. doi: 10.1007/BF01477474.
2
Placental proteins (SP1, hCG, PP5) and alpha 2-PAG in trophoblastic diseases.
Arch Gynecol. 1981;231(1):33-9. doi: 10.1007/BF02110021.