Chen Yu-Chi, Sugiyama Yasumasa, Hirota Akira
Laboratory of Applied Microbiology, School of Food and Nutritional Sciences, University of Shizuoka, Japan.
Biosci Biotechnol Biochem. 2009 Aug;73(8):1877-9. doi: 10.1271/bbb.90168. Epub 2009 Aug 7.
Two compounds were isolated from biotransformation of daidzein, a soybean isoflavone, by Aspergillus oryzae. One was 6,7,8,4'-tetrahydroxyisoflavone, an A-ring dihydroxylated daidzein, and the other was a novel compound which had the cleaved B-ring of daidzein. The former was perhaps derived from 8-hydroxydaidzein and/or 6-hydroxydaidzein, and had high DPPH radical-scavenging activity.
从米曲霉对大豆异黄酮黄豆苷元的生物转化产物中分离出两种化合物。一种是6,7,8,4'-四羟基异黄酮,即A环二羟基化的黄豆苷元,另一种是具有裂解的黄豆苷元B环的新型化合物。前者可能源自8-羟基黄豆苷元和/或6-羟基黄豆苷元,并且具有较高的1,1-二苯基-2-三硝基苯肼自由基清除活性。