Li Jianjiang, Deng Shucai, Zhao Dong, Zhao Heyuan, Sun Zhiming, Hao Yonghong, Ma Yi
Department of Spine Surgery, Tianjin Hospital, Tianjin, 300211, P.R. China.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2009 Jul;23(7):788-92.
To analyze the clinical effects of modified transforaminal lumbar interbody fusion (TLIF) for the treatment of lumbar degenerative disease.
From October 2003 to December 2006, 33 patients with lumbar degenerative disease (L3-S1) were treated by modified TLIF. There were 14 males and 19 females with an average age of 52.2 years (33 to 70 years). The median disease course was 1.8 years (4 months to 15 years). A total of 42 levels were fused, including 24 cases of single level and 9 cases of double levels. The results of preoperative diagnosis were lumbar degenerative spondylolisthesis with stenosis (8 cases), isthmic spondylolisthesis (5 cases), degenerative lumbar stenosis (16 cases), huge herniated disc with segmental instability (3 cases) and failed back surgery syndrome (1 case). During the modified TLIF procedure, total inferior facet process and inner half summit of superior facet process of TLIF side were resected to make the posterior wall of foramen opened partly. After the bone graft (3 to 5 mL) was placed into the interbody space, a single rectangle Cage was inserted obliquely from 30 degrees to 40 degrees toward the midline. Combined with pedicle screw instrumentation, TLIF was accomplished. Middle canal and opposite side nerve root decompression were performed simultaneously when necessary.
Intraoperative dura mater rupture, postoperative cerebral spinal fluid leakage, deep wound infection and transient nerve root stimulation occurred in 1 case respectively, and were all recovered after treatment. No patients had permanent neurologic deficit or aggravation. All patients were followed up for 20 to 58 months (mean 27.2 months). At the follow-up after 1 year postoperatively, all the operated segments achieved fusion standard and no broken screw or Cage dislocation occurred. All 13 cases of spondylolisthesis were reduced thoroughly and maintained satisfactorily. Nineteen patients remained slight chronic back pain. There was significant difference (P < 0.05) in JOA score between preoperation (14.9 +/- 5.1) and postoperation (25.9 +/- 3.0). The rate of clinical improvement was 80.5% (excellent in 24 cases, good in 7 cases, and fair in 2 cases).
The modified TLIF carries out the less invasive principles in opening operations, simplifies the manipulation and expands the indication of TLIF to some extent, and the clinical results for the treatment of lumbar degenerative disease is satisfactory.
分析改良经椎间孔腰椎椎体间融合术(TLIF)治疗腰椎退变性疾病的临床效果。
2003年10月至2006年12月,33例腰椎退变性疾病(L3-S1)患者接受改良TLIF治疗。男性14例,女性19例,平均年龄52.2岁(33至70岁)。疾病病程中位数为1.8年(4个月至15年)。共融合42个节段,其中单节段24例,双节段9例。术前诊断结果为腰椎退变性滑脱伴狭窄(8例)、峡部裂性滑脱(5例)、退变性腰椎管狭窄(16例)、巨大椎间盘突出伴节段性不稳(3例)和腰椎手术失败综合征(1例)。在改良TLIF手术过程中,切除TLIF侧的全部下关节突及上关节突内半侧顶点,使椎间孔后壁部分开放。在椎间间隙植入骨块(3至5 mL)后,将单个矩形椎间融合器从30度至40度向中线倾斜插入。结合椎弓根螺钉内固定,完成TLIF手术。必要时同时进行椎管中部及对侧神经根减压。
术中硬脊膜破裂、术后脑脊液漏、深部伤口感染及短暂性神经根刺激各发生1例,经治疗均恢复。无患者出现永久性神经功能缺损或加重。所有患者随访20至58个月(平均27.2个月)。术后1年随访时,所有手术节段均达到融合标准,未发生螺钉断裂或椎间融合器移位。13例滑脱患者均得到彻底复位且维持良好。19例患者仍有轻微慢性背痛。术前JOA评分(14.9±5.1)与术后(25.9±3.0)比较差异有统计学意义(P<0.05)。临床改善率为80.5%(优24例,良7例,可2例)。
改良TLIF在开放手术中贯彻了微创原则,简化了操作,在一定程度上扩大了TLIF的适应证,治疗腰椎退变性疾病的临床效果满意。