Platzer C, Siakkou H, Kraus G, Gröbel C, Rosenthal S
Central Institute of Molecular Biology, Academy of Sciences, Berlin, Buch.
Arch Exp Veterinarmed. 1990;44(6):917-23.
A monoclonal antibody (4H4) against the major internal protein, p24, of bovine leukemia virus (BLV) is described. It recognizes a sequence determinant on the p24-molecule and displays high affinity to its antigen. The monoclonal antibody 4H4 was applied in capture ELISA for diagnosis of enzootic bovine leukosis, using crude BLV-preparation as antigen. This test is more sensitive than the immunodiffusion test and at least as sensitive as direct ELISA.
本文描述了一种针对牛白血病病毒（BLV）主要内部蛋白p24的单克隆抗体（4H4）。它识别p24分子上的一个序列决定簇，并且对其抗原表现出高亲和力。单克隆抗体4H4被应用于捕获ELISA，以粗制BLV制剂作为抗原诊断地方流行性牛白血病。该检测比免疫扩散检测更灵敏，并且至少与直接ELISA一样灵敏。
Zotero 插件