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使用自体骨或骨替代物进行上颌窦底提升植入种植体的临床效果:一项系统评价

Clinical outcomes of sinus floor augmentation for implant placement using autogenous bone or bone substitutes: a systematic review.

作者信息

Nkenke Emeka, Stelzle Florian

机构信息

Department of Oral and Maxillofacial Surgery, University Hospital of Erlangen, Erlangen, Germany.

出版信息

Clin Oral Implants Res. 2009 Sep;20 Suppl 4:124-33. doi: 10.1111/j.1600-0501.2009.01776.x.

Abstract

BACKGROUND

To date, there are still no clear cut guidelines for the use of autogenous bone or bone substitutes.

AIM

The aim of the present review was to analyze the current literature in order to determine whether there are advantages of using autogenous bone (AB) over bone substitutes (BS) in sinus floor augmentation. The focused question was: is AB superior to BS for sinus floor augmentation in partially dentate or edentulous patients in terms of implant survival, patient morbidity, sinusitis, graft loss, costs, and risk of disease transmission?

MATERIALS AND METHODS

The analysis was limited to titanium implants with modified surfaces placed in sites with 6 mm of residual bone height and a lateral wall approach to the sinus. A literature search was performed for human studies focusing on sinus floor augmentation.

RESULTS

Twenty-one articles were included in the review. The highest level of evidence consisted of prospective cohort studies. A descriptive analysis of the constructed evidence tables indicated that the type of graft did not seem to be associated with the success of the procedure, its complications, or implant survival. Length of healing period, simultaneous implant placement or a staged approach or the height of the residual alveolar crest, sinusitis or graft loss did not modify the lack of effect of graft material on the outcomes. Three studies documented that there was donor site morbidity present after the harvest of AB. When iliac crest bone was harvested this sometimes required hospitalization and surgery under general anesthesia. Moreover, bone harvest extended the operating time. The assessment of disease transmission by BS was not a topic of any of the included articles.

DISCUSSION AND CONCLUSION

The retrieved evidence provides a low level of support for selection of AB or a bone substitute. Clear reasons could not be identified that should prompt the clinician to prefer AB or BS.

摘要

背景

迄今为止,对于自体骨或骨替代物的使用仍没有明确的指导方针。

目的

本综述的目的是分析当前文献,以确定在窦底提升术中使用自体骨(AB)相对于骨替代物(BS)是否存在优势。重点问题是:在部分牙列缺损或无牙患者的窦底提升术中,就种植体存活率、患者发病率、鼻窦炎、植骨块丢失、成本以及疾病传播风险而言,自体骨是否优于骨替代物?

材料与方法

分析仅限于表面经过改良的钛种植体,这些种植体植入剩余骨高度为6毫米且采用侧壁入路进入窦腔的部位。对专注于窦底提升术的人体研究进行了文献检索。

结果

该综述纳入了21篇文章。最高证据级别为前瞻性队列研究。对构建的证据表进行的描述性分析表明,植骨类型似乎与手术成功率、并发症或种植体存活率无关。愈合期长度、同期种植或分期种植方法、剩余牙槽嵴高度、鼻窦炎或植骨块丢失并未改变植骨材料对结果缺乏影响的情况。三项研究记录了采集自体骨后存在供区并发症。当采集髂嵴骨时,有时需要住院并在全身麻醉下进行手术。此外,取骨延长了手术时间。关于骨替代物疾病传播的评估并非任何一篇纳入文章的主题。

讨论与结论

检索到的证据对选择自体骨或骨替代物的支持力度较低。未能确定明确的理由促使临床医生更倾向于选择自体骨或骨替代物。

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