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先天性冠状动脉异常与外科治疗

Congenital coronary anomalies and surgical treatment.

作者信息

Kayalar Nihan, Burkhart Harold M, Dearani Joseph A, Cetta Frank, Schaff Hartzell V

机构信息

Division of Cardiovascular Surgery, Mayo Clinic, Rochester, Minn 55905, USA.

出版信息

Congenit Heart Dis. 2009 Jul-Aug;4(4):239-51. doi: 10.1111/j.1747-0803.2009.00301.x.

Abstract

Coronary artery anomalies are not uncommon, occurring in 1.3% (range = 0.3-5.6%) of the population, and are often an incidental finding in asymptomatic patients. Approximately 20% of coronary anomalies have potential for life-threatening complication, including myocardial infarction, arrhythmia, or sudden death early in life or during adulthood. Coronary artery anomalies are composed of a wide variety of disorders. Some, such as anomalous location of a coronary ostium, duplication of coronary arteries, or multiple ostia, become clinically significant only when another cardiac surgical procedure is necessary, and generally, surgical correction is not required in these patients. On the other hand, the diagnosis of anomalous origin of left coronary artery from pulmonary artery or from the opposite sinus with inter-arterial course is an indication for operation. Some anomalies like coronary artery fistulas, myocardial bridging, and coronary aneurysm require operation only when they cause clinical symptoms. Coronary artery anomalies should be included in the differential diagnosis of anginal symptoms, myocardial infarction, arrhythmia, or heart failure, especially in young patients. Increased awareness of these pathologies will lead to earlier diagnosis and treatment of a potentially life-threatening condition.

摘要

冠状动脉异常并不罕见,在人群中的发生率为1.3%(范围为0.3%-5.6%),且常在无症状患者中偶然发现。约20%的冠状动脉异常有发生危及生命并发症的可能,包括心肌梗死、心律失常或在生命早期或成年期猝死。冠状动脉异常由多种病症组成。有些,如冠状动脉口位置异常、冠状动脉重复或多个开口,仅在需要进行其他心脏手术时才具有临床意义,一般来说,这些患者不需要手术矫正。另一方面,左冠状动脉起源于肺动脉或起源于对侧窦且走行于动脉间的诊断是手术指征。一些异常,如冠状动脉瘘、心肌桥和冠状动脉瘤,仅在引起临床症状时才需要手术。冠状动脉异常应纳入心绞痛症状、心肌梗死、心律失常或心力衰竭的鉴别诊断中,尤其是在年轻患者中。提高对这些病症的认识将有助于早期诊断和治疗潜在的危及生命的疾病。

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