Université de Lyon, Lyon, France.
Epidemiol Infect. 2010 Mar;138(3):353-63. doi: 10.1017/S0950268809990562. Epub 2009 Aug 10.
The relationship between flock management and histomoniasis, a re-emergent infection in poultry, was investigated by statistical techniques used in veterinary epidemiology to deal with various problems including: multicollinearity, confounding, interaction or sample size. Associations between the variables describing flock management were examined by multivariate descriptive analysis to reduce the number of independent variables, prior to investigating associations with the disease. No homogenous groups of farms were found in the 44 free-range turkey flocks sampled in France. Histomonas meleagridis was identified in 26/38 flocks and histomoniasis was confirmed in 19 flocks. Cleanliness of the building, wet litter and diarrhoea were linked with H. meleagridis and severity of histomoniasis. Sharing outdoor fields simultaneously with chickens was related to serious macroscopic lesions determined by post-mortem examinations. Contrary to general belief, acidification of drinking water with organic acid had consistent association with the presence of H. meleagridis in turkey caeca. These results confirm previous findings and provide several new hypotheses on the effects of hygiene and water management on H. meleagridis and histomoniasis.
通过兽医流行病学中用于处理各种问题的统计技术，研究了禽类中重新出现的传染病——组织滴虫病与禽群管理之间的关系，这些问题包括：多重共线性、混杂、相互作用或样本量。通过多变量描述性分析检查了描述禽群管理的变量之间的关联，以便在调查与疾病的关联之前减少独立变量的数量。在法国抽样的 44 个自由放养火鸡禽群中，没有发现同质的农场群体。在 38 个禽群中鉴定出了火鸡组织滴虫，在 19 个禽群中确认了组织滴虫病。禽舍的清洁度、湿垫料和腹泻与 H. meleagridis 和组织滴虫病的严重程度有关。同时与鸡共享户外场地与剖检时确定的严重宏观病变有关。与普遍看法相反，有机酸酸化饮用水与火鸡盲肠中存在 H. meleagridis 有一致的关联。这些结果证实了先前的发现，并提供了关于卫生和水管理对 H. meleagridis 和组织滴虫病影响的几个新假设。
