Hollander P A
Ruth Collins Diabetes Center, Baylor University Medical Center, Dallas, TX 75246, USA.
Postgrad Med. 2000 May 15;107(6 Suppl Key):4-10. doi: 10.3810/pgm.5.15.2000.suppl4.21.
Recent advances in understanding the mechanisms of diabetes and its microvascular and macrovascular complications have mandated a much more aggressive approach to treatment. Parallel progress in developing new therapeutic agents has made that approach possible. Current recommendations underscore the importance of early management of prediabetic stages (such as impaired glucose tolerance), early diagnosis and early pharmacologic intervention, achievement of target plasma glucose levels, and use of a regimen designed for the individual patient.
在理解糖尿病及其微血管和大血管并发症机制方面的最新进展，使得采取更为积极的治疗方法成为必要。在开发新治疗药物方面取得的平行进展使这种方法成为可能。当前的建议强调了糖尿病前期阶段（如糖耐量受损）早期管理、早期诊断和早期药物干预、实现目标血糖水平以及使用针对个体患者设计的治疗方案的重要性。
