Spencer James M
Mt Sinai Hospital, New York, NY 10029, USA.
Postgrad Med. 2002 Dec;112(6 Suppl Using):17-21. doi: 10.3810/pgm.12.2002.suppl23.121.
The incidence of skin cancer exceeds that of all other cancers combined, and the trend is increasing. Around 1.2 million new cases of skin cancer are seen annually in the United States alone. The 3 major types of skin cancer commonly seen, in frequency of occurrence, include basal cell carcinoma, squamous cell carcinoma, and melanoma. All are thought to arise from cells in the epidermis, and all are most often induced by exposure to ultraviolet radiation. There is a relatively low mortality rate from cutaneous neoplasia--approximately 10,000 per year--with the majority of deaths due to malignant melanoma. However, there is a significant morbidity from these tumors, making skin cancer a major public health problem.
皮肤癌的发病率超过了所有其他癌症的总和，且呈上升趋势。仅在美国，每年就有大约120万例皮肤癌新发病例。常见的3种主要皮肤癌，按发病频率依次为基底细胞癌、鳞状细胞癌和黑色素瘤。所有这些癌症都被认为起源于表皮细胞，并且大多是由紫外线辐射诱发的。皮肤肿瘤的死亡率相对较低——每年约10000例——大多数死亡是由恶性黑色素瘤导致的。然而，这些肿瘤会造成严重的发病率，使皮肤癌成为一个重大的公共卫生问题。
