非典型抗精神病药物对血浆脂质池、胆固醇和甘油三酯的影响。
The effect of atypical antipsychotics on plasma lipid pools, cholesterol, and triglycerides.
出版信息
Postgrad Med. 2003 Dec;114(6 Suppl Managing Metabolic):80-4. doi: 10.3810/pgm.12.2003.suppl31.183.
Abstract
This article reviews published findings concerning lipid abnormalities that have been associated with the use of atypical antipsychotics. Results from both clinical studies and case series about each of the atypical antipsychotics are presented in conjunction with the few studies that have compared the lipid effects of these drugs with each other. Factors that complicate reliable assessment of the impact of antipsychotic treatment on lipid metabolism are discussed.
摘要
本文回顾了已发表的关于使用非典型抗精神病药物相关脂质异常的研究结果。文中呈现了每项非典型抗精神病药物的临床研究和病例系列结果，并结合了少数比较这些药物脂质效应的研究。还讨论了影响可靠评估抗精神病药物治疗对脂质代谢影响的复杂因素。
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