Querellou Solene, Moineau Gregory, Le Duc-Pennec Alexandra, Guillo Philippe, Turzo Alexandre, Cotonea Yann, Le Nen Dominique, Salaun Pierre-Yves
Department of Nuclear Medicine, University Hospital, Brest, France.
Nucl Med Commun. 2009 Nov;30(11):862-7. doi: 10.1097/MNM.0b013e3283306f87.
To determine the value of quantitative radioscintigraphy (QRS) in the diagnosis of wrist trauma occult fractures.
Because of the risk of non-union, the diagnosis of wrist fractures, including scaphoid fractures, is essential but remains difficult despite many imaging modalities. The aim of the study was to assess the benefits of QRS in the diagnosis of occult post-trauma wrist fractures.
This prospective study included all patients presenting at the orthopaedic department at Brest University Hospital for wrist pain after trauma with initial normal plain radiographs. Patients with normal radiographs but strongly suspected of fracture underwent QRS consisting of three-phase bone scintigraphy with quantitative analysis. When a fracture was suspected the radiograph and scintigraphy were fused to precisely locate the fracture if the index was higher than 2. If the index was lower than 1.9, fracture was excluded. Between these two indices, other investigations, such as magnetic resonance imaging, were performed. All patients were followed for at least 3 months and reviewed by the same surgeon. Patients underwent a physical examination and possibly other investigations.
From April 2006 to July 2008, 87 patients were enrolled (34 women, 53 men; median age 29 years; range, 15-87 years). Among the 46 pathologic bone scintigrams, 55 occult fractures were highlighted. At follow-up, none presented non-union. One had an undetermined QRS. Among the 40 negative results for QRS at follow-up, only one had a non-union. Sensitivity and negative predictive value were 97 and 98%, respectively for carpal fractures.
This study highlights the benefit of QRS, which allows the detection of most occult carpal fractures and reduces the risks of complications such as pseudoarthritis.
确定定量放射性核素骨显像(QRS)在诊断腕部创伤隐匿性骨折中的价值。
由于存在骨折不愈合的风险,腕部骨折(包括舟骨骨折)的诊断至关重要,但尽管有多种成像方式,诊断仍很困难。本研究的目的是评估QRS在诊断创伤后腕部隐匿性骨折中的益处。
这项前瞻性研究纳入了所有因创伤后腕部疼痛就诊于布雷斯特大学医院骨科且初始X线平片正常的患者。X线平片正常但高度怀疑骨折的患者接受了由三相骨显像及定量分析组成的QRS检查。当怀疑有骨折时,如果指数高于2,则将X线片和骨显像融合以精确定位骨折。如果指数低于1.9,则排除骨折。在这两个指数之间,则进行其他检查,如磁共振成像。所有患者至少随访3个月,并由同一位外科医生进行复查。患者接受体格检查,可能还会进行其他检查。
从2006年4月至2008年7月,共纳入87例患者(34例女性,53例男性;中位年龄29岁;范围15 - 87岁)。在46例病理性骨显像中,发现了55例隐匿性骨折。随访时,无一例出现骨折不愈合。1例QRS结果未明确。在随访时QRS结果为阴性的40例患者中,只有1例出现骨折不愈合。腕骨骨折的敏感性和阴性预测值分别为97%和98%。
本研究突出了QRS的益处,它能够检测出大多数隐匿性腕骨骨折,并降低了诸如创伤性关节炎等并发症的风险。