[肝脏染色质脱氧核糖核酸酶对PM-2噬菌体和猿猴病毒40闭环DNA的作用]
[Effect of liver chromatin DNAse on closed circular DNA of PM-2 phage and simian virus 40].
作者信息
Vinter V G, Beliaeva M I, Shliankevich M A, Khamidullina N G, Polotskaia A V, Zotkina N G
出版信息
Biokhimiia. 1977 May;42(5):823-7.
PMID:196682
Abstract
Comparative effect of the DNAse from rat liver chromatin and Neurospora crassa endonuclease S1 on closed circular superhelical DNA of PM-2 phage and Simian Virus 40 is studied. It is shown that both of them--the DNAse from chromatin proteins and endonuclease S1--are specific to single-stranded regions in DNA molecular. It is suggested that chromatin protein DNAse participates in reparation processes.
摘要
研究了大鼠肝脏染色质中的脱氧核糖核酸酶（DNAse）和粗糙脉孢菌核酸内切酶S1对PM - 2噬菌体和猿猴病毒40的闭环超螺旋DNA的比较作用。结果表明，它们两者——染色质蛋白中的DNAse和核酸内切酶S1——对DNA分子中的单链区域具有特异性。有人提出染色质蛋白DNAse参与修复过程。
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