Rink B, Becker D
Klinik für Kiefer- und Gesichtschirurgie der Humboldt-Universität Berlin.
Dtsch Z Mund Kiefer Gesichtschir. 1990 Nov-Dec;14(6):450-5.
The clinical behavior of 51 adenoid cystic carcinomas of the salivary glands demonstrated a protracted and partly insidious course of disease with obstinately recurring tumors and a high tendency for distant metastases. The tumors are mainly localized in the minor salivary glands, invasion and growth along adjoining nerves are characteristic of these tumors. With increasing size of the tumor the prognosis significantly deteriorates. The treatment of choice is radical surgery, possibly combined with irradiation. A treatment of both the primary tumor and the recurrent tumor is of benefit in the presence of distant metastases, because the latter remains clinically symptomless for years. Because of the protraction of the disease the importance of early detection of these tumors is pointed out.
51例涎腺腺样囊性癌的临床行为显示，疾病过程迁延且部分隐匿，肿瘤顽固复发，远处转移倾向高。肿瘤主要位于小涎腺，沿相邻神经浸润和生长是这些肿瘤的特征。随着肿瘤体积增大，预后明显恶化。首选治疗方法是根治性手术，可能联合放疗。对于存在远处转移的患者，对原发肿瘤和复发性肿瘤都进行治疗是有益的，因为后者多年来临床上无症状。由于疾病的迁延，指出了早期发现这些肿瘤的重要性。
