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基于玻片的细胞计数法的临床应用——最新进展

Clinical applications of slide-based cytometry--an update.

作者信息

Gerstner Andreas O H, Laffers Wiebke, Tárnok Attila

机构信息

Department of Otorhinolaryngology/Head and Neck Surgery, University of Bonn, Sigmund-Freud-Str. 25, 53105 Bonn, Germany.

出版信息

J Biophotonics. 2009 Sep;2(8-9):463-9. doi: 10.1002/jbio.200910029.

Abstract

Slide-based cytometric approaches open the possibility to obtain quantitative and objective data from specimens that so far have not been accessible to this kind of analysis. In this review, we will highlight the specific advantages of slide-based cytometry (SBC) and show the applications that have been established for clinical samples. Focuses are cytomic analyses of oncological and hematological samples where the slide-based concept turned out to open new dimensions in understanding underlying cellular networks. We review the recent literature and point out future applications.

摘要

基于玻片的细胞计数方法为从迄今无法进行此类分析的标本中获取定量和客观数据提供了可能性。在本综述中,我们将重点介绍基于玻片的细胞计数法(SBC)的具体优势,并展示已在临床样本中确立的应用。重点是肿瘤学和血液学样本的细胞组学分析,其中基于玻片的概念在理解潜在细胞网络方面开辟了新的维度。我们回顾了近期文献并指出了未来的应用。

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