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[DNA vaccines and recombinant antigens in prevention of Toxoplasma gondii infections--current status of the studies].

作者信息

Hiszczyńska-Sawicka Elzbieta, Holec-Gasior Lucyna, Kur Józef

机构信息

Katedra Mikrobiologii, Politechnika Gdańska, ul. G. Narutowicza 11/12, 80-952 Gdańsk.

出版信息

Wiad Parazytol. 2009;55(2):125-39.

PMID:19670528
Abstract

Toxoplasmosis caused by an intracellular parasite Toxoplasma gondii is still one of major medical and veterinary problems and there is still need for a vaccine for human toxoplasmosis. Despite years of research much remains to be done to develop effective vaccine. The article presents the current status of vaccine strategies against toxoplasmosis with focus on the most developed approaches using naked DNA and recombinant antigens.

摘要

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Wiad Parazytol. 2009;55(2):125-39.
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Korean J Parasitol. 2018 Aug;56(4):325-334. doi: 10.3347/kjp.2018.56.4.325. Epub 2018 Aug 31.
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Immune responses and protection after DNA vaccination against Toxoplasma gondii calcium-dependent protein kinase 2 (TgCDPK2).针对刚地弓形虫钙依赖性蛋白激酶2(TgCDPK2)进行DNA疫苗接种后的免疫反应与保护作用。
Parasite. 2017;24:41. doi: 10.1051/parasite/2017045. Epub 2017 Nov 9.
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DNA Vaccines Encoding Toxoplasma gondii Cathepsin C 1 Induce Protection against Toxoplasmosis in Mice.
编码刚地弓形虫组织蛋白酶C 1的DNA疫苗可诱导小鼠对弓形虫病产生保护作用。
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Protection via a ROM4 DNA vaccine and peptide against Toxoplasma gondii in BALB/c mice.通过ROM4 DNA疫苗和肽对BALB/c小鼠进行抗弓形虫保护。
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