Minami Kazuhiko, Hasegawa Naoko, Fukuoka Osamu, Miyajima Chie, Tsunoda Reiko, Fukaya Takashi
Kanto Medical Center NTT-EC Department of Otolaryngology, Tokyo.
Nihon Jibiinkoka Gakkai Kaiho. 2009 Jul;112(7):550-3. doi: 10.3950/jibiinkoka.112.550.
Mohs' chemosurgery, originally developed to treat skin cancer, uses zinc chloride in Mohs' ointment to fix tissues, and is applicable in different clinical settings. In advanced head and neck cancer, Mohs' chemosurgery relieves main skin-infiltration symptoms such as bleeding, infection, exudation, and severe pain. Mohs' chemosurgery conducted in two cases of advanced head and neck cancer yielded an acceptable result free of bleeding, pain, exudation, and infection. Steps in palliative care are repeated until the tumor surface is completely fixed. Using Mohs' ointment provides acceptable relief without technical complications. Although not a topical chemotherapeutic agent, it fixes the lesion well.
莫氏化学外科手术最初是为治疗皮肤癌而开发的，在莫氏软膏中使用氯化锌来固定组织，适用于不同的临床情况。在晚期头颈癌中，莫氏化学外科手术可缓解主要的皮肤浸润症状，如出血、感染、渗出和剧痛。对两例晚期头颈癌患者实施莫氏化学外科手术，取得了可接受的效果，无出血、疼痛、渗出和感染。重复姑息治疗步骤，直到肿瘤表面完全固定。使用莫氏软膏可提供可接受的缓解效果，且无技术并发症。虽然它不是局部化疗药物，但能很好地固定病变。
