Maeda Takahiro, Kozakai Norihide, Nishiyama Tooru, Sugiura Hitoshi, Nakamura Kaoru
The Department of Urology, Kawasaki Municipal Hospital.
Hinyokika Kiyo. 2009 Jul;55(7):409-12.
Pheochromocytoma is a catecholamine-secreting tumor which provokes various symptoms such as episodic headache, sweating and tachycardia. Meanwhile patients with hemodialysis have similar symptoms. Additionally patients with chronic renal failure often can not take the 24-hour urine collection test. Therefore it is said to be difficult to diagnose pheochromocytoma in patients with end stage renal disease. We present herein a case of a woman with hemodialysis discovered to have a pheochromocytoma. A 48-year-old female was admitted to our hospital due to paroxysmal hypertension during hemodialysis. Plasma dopamine and noradrenaline were slightly elevated. Computerized tomography revealed a 2 cm round mass at left adrenal gland. 131I-MIBG scintiscan detected that tumor at the same lesion. Under the diagnosis of pheochromocytoma, she had taken alpha-adrenergic blocking agent for 4 weeks and left adrenalectomy was successfully performed.
嗜铬细胞瘤是一种分泌儿茶酚胺的肿瘤,可引发各种症状,如发作性头痛、出汗和心动过速。同时,血液透析患者也有类似症状。此外,慢性肾衰竭患者往往无法进行24小时尿收集试验。因此,据说在终末期肾病患者中诊断嗜铬细胞瘤很困难。我们在此报告一例血液透析女性被发现患有嗜铬细胞瘤的病例。一名48岁女性因血液透析期间阵发性高血压入院。血浆多巴胺和去甲肾上腺素略有升高。计算机断层扫描显示左肾上腺有一个2厘米的圆形肿块。131I-MIBG闪烁扫描在同一病变处检测到肿瘤。在诊断为嗜铬细胞瘤后,她服用了α-肾上腺素能阻滞剂4周,并成功进行了左肾上腺切除术。