Suppr超能文献

[终末期肾病患者接受腹膜透析治疗时的嗜铬细胞瘤]

[Pheochromocytoma in end-stage renal disease patient treated by peritoneal dialysis].

作者信息

Gorsane Imen, Zouaghi Karim, Goucha Rim, Bacha Mohamed Mongi, Hedri Hafedh, Khiari Karima, Abderrahim Ezzedine, Abdallah Taieb Ben, Abdallah Nejib Ben, Moussa Fatma Ben, Maiz Hedi Ben, Kheder Adel

机构信息

Service de néphrologie et de médecine interne A, hôpital Charles-Nicolle, boulevard 9-Avril, BS 1006, Tunis, Tunisie.

出版信息

Nephrol Ther. 2008 Dec;4(7):597-601. doi: 10.1016/j.nephro.2008.05.002. Epub 2008 Jul 31.

Abstract

Pheochromocytoma is a rare tumor responsible for paroxysmal hypertension which is difficult to control. Diagnosis is important because it represents a curable form of hypertension. Few cases of pheochromocytoma patients with end-stage renal failure were reported in the literature. These cases are specially responsible for diagnosis and therapeutic problems. We report here a case of an end-stage renal failure patient who has pheochromocytoma, he was treated by automated peritoneal dialysis. The patient is a 47-year-old man who has an IgA glomerulonephritis. On peritoneal dialysis, his blood pressure level remains high despite four antihypertensive drugs association and adequate dialysis. Furthermore, the patient suffered from headaches, sweats and palpitations. This leads to suspect pheochromocytoma. Thus, urinary excretion rates of metanephrines and normetanephrines were high. Radiographic diagnosis tests were negative but MIBG scintigraphy was able to localise the tumor in the left suprarenal gland. He had coelioscopic left adrenalectomy without complications, microscopic studies showed an hyperplasia of the adrenal medulla. Soon after surgery his blood pressure was well controlled by one antihypertensive drug. We conclude that refractory hypertension, as a possible diagnosis, is uncommon in peritoneal dialysis patients. Pheochromocytoma must be eliminated by careful evaluation.

摘要

嗜铬细胞瘤是一种导致难以控制的阵发性高血压的罕见肿瘤。诊断很重要,因为它代表了一种可治愈的高血压形式。文献中报道的终末期肾衰竭嗜铬细胞瘤患者病例很少。这些病例特别容易引发诊断和治疗问题。我们在此报告一例患有嗜铬细胞瘤的终末期肾衰竭患者,他接受了自动腹膜透析治疗。该患者是一名47岁男性,患有IgA肾小球肾炎。在进行腹膜透析时,尽管联合使用了四种抗高血压药物且透析充分,但他的血压水平仍然很高。此外,该患者还患有头痛、出汗和心悸。这导致怀疑患有嗜铬细胞瘤。因此,间甲肾上腺素和去甲间甲肾上腺素的尿排泄率很高。影像学诊断检查结果为阴性,但MIBG闪烁扫描能够将肿瘤定位在左肾上腺。他接受了腹腔镜左肾上腺切除术,没有出现并发症,显微镜检查显示肾上腺髓质增生。手术后不久,他的血压通过一种抗高血压药物就得到了很好的控制。我们得出结论,作为一种可能的诊断,难治性高血压在腹膜透析患者中并不常见。必须通过仔细评估排除嗜铬细胞瘤。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验