RTI International, Atlanta, GA 30341, USA.
J Viral Hepat. 2010 Jan;17(1):28-33. doi: 10.1111/j.1365-2893.2009.01165.x. Epub 2009 Aug 6.
The Centers for Disease Control and Prevention (CDC) recommends hepatitis B surface antigen (HBsAg) testing to identify hepatitis B virus (HBV) infection for foreign-born persons from areas with HBsAg prevalence of > or = 2%. Currently, most HBsAg screening in the United States is performed by independent community organizations. For these HBsAg screening programs, we collected information about the location, number of people screened, other services beyond screening provided, the population/ethnicity groups targeted for screening, and the prevalence of HBsAg among those screened. We identified programs offering screening by contacting programs known to us, from interviews with identified programs, and from structured Internet searches, and collected information using a simple e-mail survey with follow-up phone calls. We identified 55 possible community HBsAg screening programs, of which we successfully contacted 31 programs. In the past year, contacted programs screened an estimated 21 817 patients with an 8.1% average HBsAg prevalence. The majority of programs screened persons born in Asia and their children, and a small number of programs screened persons from Africa or Eastern Europe; very few programs screened U.S.-born persons at risk of HBV infection due to behavioural factors. We identified few or no programs in the American Southeast, the Midwest, and the Southwest outside of California and the Houston area. The HBsAg screening programs that we contacted were effective in identifying and screening patients at risk of HBV as evidenced by the high prevalence observed among those screened. However, their efforts alone are likely insufficient to meet the need for screening recommended by CDC.
疾病预防控制中心(CDC)建议使用乙肝表面抗原(HBsAg)检测来识别乙型肝炎病毒(HBV)感染,对象为来自 HBsAg 流行率大于等于 2%的地区的外国出生者。目前,美国大多数 HBsAg 筛查都是由独立的社区组织进行的。对于这些 HBsAg 筛查项目,我们收集了有关位置、筛查人数、筛查以外的其他服务、筛查对象的人口/族群以及筛查人群中 HBsAg 流行率的信息。我们通过联系已知的项目、对已确定的项目进行访谈以及通过结构化的互联网搜索来确定提供筛查的项目,并使用简单的电子邮件调查和后续电话联系来收集信息。我们确定了 55 个可能的社区 HBsAg 筛查项目,其中成功联系了 31 个项目。在过去的一年中,联系的项目估计对 21817 名患者进行了筛查,平均 HBsAg 流行率为 8.1%。大多数项目筛查的是出生在亚洲的人和他们的孩子,少数项目筛查的是来自非洲或东欧的人;很少有项目筛查由于行为因素而有感染 HBV 风险的美国出生者。我们在美国东南部、中西部和加利福尼亚州和休斯顿地区以外的西南部发现的项目很少或没有。我们联系的 HBsAg 筛查项目在识别和筛查有 HBV 感染风险的患者方面非常有效,这从筛查人群中观察到的高流行率就可以证明。然而,仅靠他们的努力可能不足以满足 CDC 推荐的筛查需求。