Zhang John, Bateman Rebecca, Metzger Shastidy, Lanigan Kurt
Associate Professor, Logan College of Chiropractic, Chesterfield, MO.
J Chiropr Med. 2006 Summer;5(2):53-9. doi: 10.1016/S0899-3467(07)60133-5.
To study the effects of a nutritional supplement on cardiovascular health determined by blood and saliva biochemistry and heart rate variability (HRV) in asymptomatic college students and faculty members.
Forty subjects were recruited in the study via a school wide email notification and through personal contacts. GreensFirst vegetable supplement drink was tested to document its effect on the blood and saliva biochemistry in relation to cardiovascular health.
After taking the supplement for 90 days, both the systolic and diastolic blood pressure decreased significantly. The heart rate decreased but did not reach statistical significance. Time domain analysis of HRV showed a slight decrease in standard deviation of normal-normal and square root of the mean squared differences but did not reach statistical significance. Frequency analysis of HRV found no significant changes. Saliva dehydroepiandosterone sulfate (DHEA-S) and Cortisol decreased after taking the supplement, however, they did not reach significant levels. Blood glucose concentration was increased slightly but the change was not significant. Blood serum tests showed no significant changes in the total cholesterol or the low-density lipoprotein levels. However, it was noted that the high-density lipoprotein level was decreased significantly. Triglycerides did not show any significant changes but it were slightly elevated after the treatment period. Homocysteine increased significantly after taking the supplement for 90 days.
For this group of subjects, taking the green vegetable drink for 90 days reduced blood pressure but did not significantly affect the blood and saliva chemistry.
通过血液和唾液生化指标以及心率变异性(HRV)研究营养补充剂对无症状大学生和教职工心血管健康的影响。
通过全校范围的电子邮件通知和个人联系招募了40名受试者。对GreensFirst蔬菜补充剂饮料进行测试,以记录其对与心血管健康相关的血液和唾液生化指标的影响。
服用补充剂90天后,收缩压和舒张压均显著下降。心率下降,但未达到统计学显著性。HRV的时域分析显示,正常到正常间期标准差和均方根差略有下降,但未达到统计学显著性。HRV的频域分析未发现显著变化。服用补充剂后,唾液硫酸脱氢表雄酮(DHEA-S)和皮质醇下降,但未达到显著水平。血糖浓度略有升高,但变化不显著。血清检测显示总胆固醇或低密度脂蛋白水平无显著变化。然而,注意到高密度脂蛋白水平显著下降。甘油三酯未显示任何显著变化,但在治疗期后略有升高。服用补充剂90天后,同型半胱氨酸显著增加。
对于这组受试者,服用绿色蔬菜饮料90天可降低血压,但对血液和唾液生化指标无显著影响。