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关于在医学研究分析中使用非参数威尔科克森-曼-惠特尼检验的说明。

A note on the use of the non-parametric Wilcoxon-Mann-Whitney test in the analysis of medical studies.

作者信息

Kühnast Corinna, Neuhäuser Markus

机构信息

Institute for Medical Informatics, Biometry and Epidemiology, University of Duisburg-Essen, Essen, Germany.

出版信息

Ger Med Sci. 2008 Apr 7;6:Doc02.

PMID:19675730
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2703264/
Abstract

BACKGROUND

Although non-normal data are widespread in biomedical research, parametric tests unnecessarily predominate in statistical analyses.

METHODS

We surveyed five biomedical journals and - for all studies which contain at least the unpaired t-test or the non-parametric Wilcoxon-Mann-Whitney test - investigated the relationship between the choice of a statistical test and other variables such as type of journal, sample size, randomization, sponsoring etc.

RESULTS

The non-parametric Wilcoxon-Mann-Whitney was used in 30% of the studies. In a multivariable logistic regression the type of journal, the test object, the scale of measurement and the statistical software were significant. The non-parametric test was more common in case of non-continuous data, in high-impact journals, in studies in humans, and when the statistical software is specified, in particular when SPSS was used.

摘要

背景

尽管非正态数据在生物医学研究中广泛存在,但参数检验在统计分析中仍不必要地占据主导地位。

方法

我们调查了五本生物医学期刊,并针对所有至少包含未配对t检验或非参数Wilcoxon-Mann-Whitney检验的研究,调查了统计检验的选择与其他变量(如期刊类型、样本量、随机化、资助等)之间的关系。

结果

30%的研究使用了非参数Wilcoxon-Mann-Whitney检验。在多变量逻辑回归中,期刊类型、检验对象、测量尺度和统计软件具有显著性。非参数检验在非连续数据、高影响力期刊、人体研究以及指定统计软件(特别是使用SPSS时)的情况下更为常见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abb9/2703264/68d9ee3eb849/GMS-06-02-t-003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abb9/2703264/26560171a4f5/GMS-06-02-t-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abb9/2703264/a6f258f0cd35/GMS-06-02-t-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abb9/2703264/68d9ee3eb849/GMS-06-02-t-003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abb9/2703264/26560171a4f5/GMS-06-02-t-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abb9/2703264/a6f258f0cd35/GMS-06-02-t-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abb9/2703264/68d9ee3eb849/GMS-06-02-t-003.jpg

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