[亚硝基化合物前体给予大鼠后维生素A对肝脏解毒谷胱甘肽系统酶活性的影响]
[Effects of vitamin A on the activity of glutathione system enzymes of liver detoxication after administration of nitroso-compound precursors to rats].
作者信息
Pentiuk A A, Vinarchuk M P, Boreĭko N R
出版信息
Eksp Onkol. 1990;12(1):19-21.
PMID:1967575
Abstract
The activity of glutathione system enzymes exposed to nitroso-compound (NC) precursors in small doses for 12 months and preliminary injection of vitamin A have been studied. The histo- and biochemical examinations have revealed a pronounced increase in the enzyme activity exposed of NC precursors and a slight increase when injecting preliminary vitamin A.
摘要
研究了小剂量亚硝基化合物（NC）前体暴露12个月以及预先注射维生素A后谷胱甘肽系统酶的活性。组织学和生化检查显示，暴露于NC前体时酶活性显著增加，而预先注射维生素A时酶活性略有增加。
相似文献
1
2
Induction of tumors of the nasal cavity in rats by concurrent feeding of thiram and sodium nitrite.
J Toxicol Environ Health. 1984;13(4-6):609-14. doi: 10.1080/15287398409530525.
3
4
5
6
Effect of lithium on hepatic drug-metabolizing enzymes of protein-deficient rats.
Biol Trace Elem Res. 1997 Winter;59(1-3):159-65. doi: 10.1007/BF02783241.
7
Role of glutathione metabolizing enzymes in nickel mediated induction of hepatic glutathione.
Res Commun Chem Pathol Pharmacol. 1987 Sep;57(3):421-4.
8
9
[Effect of silimarine on activity of lysosomal proteinases in the liver and kidneys during tetramethylthiuram disulfide administration].
Vopr Med Khim. 1988 Sep-Oct;34(5):110-3.
Zotero 插件