Moghadam-Kia Siamak, Nawaz Asad, Millar B Cherie, Moore John E, Wiegers Susan E, Torigian Drew A, Basu Sandip, Alavi Abass
Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.
Hell J Nucl Med. 2009 May-Aug;12(2):165-7.
Echocardiography (EC) plays a major role in diagnosing and monitoring the therapeutic response in infective endocarditis (IE) in routine practice. However in the setting of prosthetic valves or indwelling pacemakers, the EC findings are equivocal necessitating search for other diagnostic modalities. In these patients, (18)F-FDG/PET imaging may prove invaluable as evidenced by the presented case. We herein report a case of an 82 years old male with a mechanical aortic valve prosthesis who presented with a 10 days history of fever and malaise. Optimal interpretation of the EC results was difficult due to the presence of the prosthetic valve. However, (18)F-FDG-PET imaging findings were quite distinctive and revealed abnormally increased metabolic activity represented by two foci of increased (18)F-FDG uptake in the right and left borders of the heart that corresponded to areas of IE.
在常规实践中，超声心动图（EC）在感染性心内膜炎（IE）的诊断和治疗反应监测中起着主要作用。然而，在人工瓣膜或植入式起搏器的情况下，EC检查结果不明确，需要寻找其他诊断方法。如本病例所示，在这些患者中，（18）F-FDG/PET成像可能被证明具有极高的价值。我们在此报告一例82岁男性患者，他植入了机械主动脉瓣膜假体，出现发热和不适10天。由于存在人工瓣膜，难以对EC结果进行最佳解读。然而，（18）F-FDG-PET成像结果非常独特，显示代谢活性异常增加，表现为心脏左右边界有两个（18）F-FDG摄取增加的病灶，对应于IE区域。
